What do you do when the world declares something impossible? When physician-scientist David Fajgenbaum was dying from a rare disease and social entrepreneur Kiah Williams was confronting the realities of economic hardship, they began asking a different question: What can I do today? In this conversation, they discuss how turning hope into action can drive meaningful change — one step at a time. (This conversation is hosted by The Audacious Project’s Alexandra Tillmann) (Recorded at TEDNext 2025 on November 10, 2025.)

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The TED Idea Search wraps up in Amman, Jordan, in a 2,000-year-old Roman amphitheater and in front of a crowd of 4,000. What unfolds inside those stone walls is something the series hasn’t quite seen before: speakers shaped by the weight of living in a region the world tends to define for itself. From a mountaineer who turned grief into motivation to a therapist rewriting the Arab world’s language around mental health, the final city makes the strongest case yet that the best ideas can come from anywhere.

Watch the full talks from the TEDxAmman Idea Search:

00:00 – Intro
3:24 – Rehearsals
16:00 – The Talks
36:28 – Deliberation
38:48 – The Winner Is…

The most interesting ideas often come from the most unexpected places. We searched the globe for ideas with the power to inspire, motivate and change lives — and we found them at @TEDx events around the world. The TED Idea Search follows extraordinary speakers from 9 countries competing for a spot on the TED main stage in Vancouver this April.

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The TED Talks channel features the best talks and performances from the TED Conference, where the world’s leading thinkers and doers give the talk of their lives in 18 minutes (or less) — plus originals, podcasts and exclusive content. Look for videos on Technology, Entertainment and Design as well as science, business, global issues, the arts and more. Visit for our entire library, transcripts, translations and personalized recommendations.

TED videos may be used for non-commercial purposes under a Creative Commons License, Attribution–Non Commercial–No Derivatives (or the CC BY – NC – ND 4.0 International) and in accordance with the TED Talks Usage Policy: . For more information on using TED for commercial purposes (e.g. employee learning, in a film or online course), submit a request at

#TED #TEDTalks #TEDIdeaSearch