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How Do You Turn Setbacks Into Motivation? A Doctor + A Trauma Specialist Answer | TED Intersections

How do you hold on to hope while still being realistic about the work that needs to be done? Immunology researcher David Fajgenbaum and public health expert Celina de Sola discuss how they scaled personal missions into organizations making long-term impact on communities near and far. They explore how to stay motivated, discover your leadership…

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How do you hold on to hope while still being realistic about the work that needs to be done? Immunology researcher David Fajgenbaum and public health expert Celina de Sola discuss how they scaled personal missions into organizations making long-term impact on communities near and far. They explore how to stay motivated, discover your leadership style and uncover overlooked solutions hiding in plain sight. (This conversation is part of “TED Intersections,” a series featuring thought-provoking conversations between experts navigating the ideas shaping our world.)

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The TED Talks channel features talks, performances and original series from the world’s leading thinkers and doers. Subscribe to our channel for videos on Technology, Entertainment and Design — plus science, business, global issues, the arts and more. Visit to get our entire library of TED Talks, transcripts, translations, personalized talk recommendations and more.

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11 Comments

11 Comments

  1. @LoriMcalroy

    September 23, 2025 at 11:01 am

    Hey Ted 👋

  2. @LoriMcalroy

    September 23, 2025 at 11:04 am

    This couldn’t be more needed trauma n stress anxiety’s my middle name can’t believe im still here

  3. @LoriMcalroy

    September 23, 2025 at 11:07 am

    I was thinking this yesterday when it came to ibs and gastrics problems

  4. @Leto2ndAtreides

    September 23, 2025 at 12:09 pm

    What drug did you use for your Castleman disease?

  5. @TheBestLifeMindsetWithShelly

    September 23, 2025 at 1:24 pm

    Inspiring conversation! I love the focus on turning hope into concrete action, such a powerful reminder that small, consistent steps create real change. 💖

  6. @claires9100

    September 23, 2025 at 1:27 pm

    Holding despair and hope together is a very powerful concept. Hope in action is so important. This really resonates with me .

  7. @MaiAnnChan

    September 23, 2025 at 2:58 pm

    Truly inspiring story,just what my nephew is doing in Toronto, Canada, smart man❤❤❤❤❤

  8. @MaiAnnChan

    September 23, 2025 at 2:59 pm

    Great for those who are able to give their own TED talk❤❤❤❤😊🎉🎉❤❤

  9. @innerrise.official

    September 23, 2025 at 7:58 pm

    It’s truly inspiring to hear how two incredible individuals are turning hope into tangible action, tackling massive challenges in healthcare and social systems.

  10. @todaycountsshow

    September 24, 2025 at 4:39 am

    Holding hope and despair together fuels resilience, purpose, and meaningful impact. 🌱

  11. @KkKk-t2c7d

    September 24, 2025 at 6:30 am

    My friend, I find that formal British English, like what we hear on the BBC, is clear and beautiful. But I also understand that it’s important to learn both formal and casual English at the same time.

    The challenge is that British casual English feels very difficult for me, and there are so many different regional accents.

    So my question is: would it be acceptable to focus on formal British English, while also learning American casual English? I feel that American casual English is much easier to follow than British casual English.!

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Your body is build for movement — so make it a part of your day #TEDTalks

Can a five-minute walk change how you feel all day? Exercise scientist Keith Diaz shows how your body is built for the kind of movement that modern life has quietly erased — and suggests something refreshingly doable: making time for small doses of movement sprinkled throughout the day, as a way to boost your brain…

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Can a five-minute walk change how you feel all day? Exercise scientist Keith Diaz shows how your body is built for the kind of movement that modern life has quietly erased — and suggests something refreshingly doable: making time for small doses of movement sprinkled throughout the day, as a way to boost your brain and body.

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Inside Dubai’s Mission to Build the City of the Future | His Excellency Khalfan Belhoul | TED

What does it look like when a city becomes a laboratory for innovation? His Excellency Khalfan Belhoul, CEO of the Dubai Future Foundation, explains why Dubai is cutting the bureaucratic red tape to experiment with big ideas in everything from AI and emerging tech to finance and climate solutions. The future, he says, depends on…

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What does it look like when a city becomes a laboratory for innovation? His Excellency Khalfan Belhoul, CEO of the Dubai Future Foundation, explains why Dubai is cutting the bureaucratic red tape to experiment with big ideas in everything from AI and emerging tech to finance and climate solutions. The future, he says, depends on those willing to test it. (This conversation is hosted by TED’s Whitney Pennington Rodgers.) (Recorded at TED@BCG on October 23, 2025)

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The TED Talks channel features the best talks and performances from the TED Conference, where the world’s leading thinkers and doers give the talk of their lives in 18 minutes (or less) — plus originals, podcasts and exclusive content. Look for videos on Technology, Entertainment and Design as well as science, business, global issues, the arts and more. Visit for our entire library, transcripts, translations and personalized recommendations.

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The Iran war has cost billions — but its toll goes far beyond the global economy says @Ian_Bremmer

Six months into a catastrophic war in Iran — and with no end in sight for the war in Ukraine — the world is embroiled in conflicts with no apparent exit plan. In this interview, political scientist and Eurasia Group founder Ian Bremmer breaks down what these wars are costing people around the world —…

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Six months into a catastrophic war in Iran — and with no end in sight for the war in Ukraine — the world is embroiled in conflicts with no apparent exit plan. In this interview, political scientist and Eurasia Group founder Ian Bremmer breaks down what these wars are costing people around the world — and which one he’s more worried might spiral out of control. (This interview, hosted by TED’s Helen Walters, was recorded on July 28, 2026.)

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