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How Do You Turn Setbacks Into Motivation? A Doctor + A Trauma Specialist Answer | TED Intersections

How do you hold on to hope while still being realistic about the work that needs to be done? Immunology researcher David Fajgenbaum and public health expert Celina de Sola discuss how they scaled personal missions into organizations making long-term impact on communities near and far. They explore how to stay motivated, discover your leadership…

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How do you hold on to hope while still being realistic about the work that needs to be done? Immunology researcher David Fajgenbaum and public health expert Celina de Sola discuss how they scaled personal missions into organizations making long-term impact on communities near and far. They explore how to stay motivated, discover your leadership style and uncover overlooked solutions hiding in plain sight. (This conversation is part of “TED Intersections,” a series featuring thought-provoking conversations between experts navigating the ideas shaping our world.)

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11 Comments

11 Comments

  1. @LoriMcalroy

    September 23, 2025 at 11:01 am

    Hey Ted 👋

  2. @LoriMcalroy

    September 23, 2025 at 11:04 am

    This couldn’t be more needed trauma n stress anxiety’s my middle name can’t believe im still here

  3. @LoriMcalroy

    September 23, 2025 at 11:07 am

    I was thinking this yesterday when it came to ibs and gastrics problems

  4. @Leto2ndAtreides

    September 23, 2025 at 12:09 pm

    What drug did you use for your Castleman disease?

  5. @TheBestLifeMindsetWithShelly

    September 23, 2025 at 1:24 pm

    Inspiring conversation! I love the focus on turning hope into concrete action, such a powerful reminder that small, consistent steps create real change. 💖

  6. @claires9100

    September 23, 2025 at 1:27 pm

    Holding despair and hope together is a very powerful concept. Hope in action is so important. This really resonates with me .

  7. @MaiAnnChan

    September 23, 2025 at 2:58 pm

    Truly inspiring story,just what my nephew is doing in Toronto, Canada, smart man❤❤❤❤❤

  8. @MaiAnnChan

    September 23, 2025 at 2:59 pm

    Great for those who are able to give their own TED talk❤❤❤❤😊🎉🎉❤❤

  9. @innerrise.official

    September 23, 2025 at 7:58 pm

    It’s truly inspiring to hear how two incredible individuals are turning hope into tangible action, tackling massive challenges in healthcare and social systems.

  10. @todaycountsshow

    September 24, 2025 at 4:39 am

    Holding hope and despair together fuels resilience, purpose, and meaningful impact. 🌱

  11. @KkKk-t2c7d

    September 24, 2025 at 6:30 am

    My friend, I find that formal British English, like what we hear on the BBC, is clear and beautiful. But I also understand that it’s important to learn both formal and casual English at the same time.

    The challenge is that British casual English feels very difficult for me, and there are so many different regional accents.

    So my question is: would it be acceptable to focus on formal British English, while also learning American casual English? I feel that American casual English is much easier to follow than British casual English.!

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How to Invite Creativity into Your Life | Rose B. Simpson, Debbie Millman | TED

What do you hear when you sit in silence? For artist Rose B. Simpson, that question is the beginning of all art. She comes from a line of ceramic artists stretching back generations and, as part of her multidisciplinary work, she also builds custom lowrider cars. (If that sounds like a contradiction, that’s kind of…

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What do you hear when you sit in silence? For artist Rose B. Simpson, that question is the beginning of all art. She comes from a line of ceramic artists stretching back generations and, as part of her multidisciplinary work, she also builds custom lowrider cars. (If that sounds like a contradiction, that’s kind of the point.) In conversation with “Design Matters” podcast host Debbie Millman, Simpson invites you to find your own aesthetic — not by searching, but by listening. (Recorded at TEDNext 2025 on November 10, 2025)

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The TED Talks channel features the best talks and performances from the TED Conference, where the world’s leading thinkers and doers give the talk of their lives in 18 minutes (or less) — plus originals, podcasts and exclusive content. Look for videos on Technology, Entertainment and Design as well as science, business, global issues, the arts and more. Visit for our entire library, transcripts, translations and personalized recommendations.

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The reality is that democracies depend on one another to survive #TEDTalks

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