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How Do You Turn Setbacks Into Motivation? A Doctor + A Trauma Specialist Answer | TED Intersections

How do you hold on to hope while still being realistic about the work that needs to be done? Immunology researcher David Fajgenbaum and public health expert Celina de Sola discuss how they scaled personal missions into organizations making long-term impact on communities near and far. They explore how to stay motivated, discover your leadership…

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How do you hold on to hope while still being realistic about the work that needs to be done? Immunology researcher David Fajgenbaum and public health expert Celina de Sola discuss how they scaled personal missions into organizations making long-term impact on communities near and far. They explore how to stay motivated, discover your leadership style and uncover overlooked solutions hiding in plain sight. (This conversation is part of “TED Intersections,” a series featuring thought-provoking conversations between experts navigating the ideas shaping our world.)

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The TED Talks channel features talks, performances and original series from the world’s leading thinkers and doers. Subscribe to our channel for videos on Technology, Entertainment and Design — plus science, business, global issues, the arts and more. Visit to get our entire library of TED Talks, transcripts, translations, personalized talk recommendations and more.

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11 Comments

11 Comments

  1. @LoriMcalroy

    September 23, 2025 at 11:01 am

    Hey Ted 👋

  2. @LoriMcalroy

    September 23, 2025 at 11:04 am

    This couldn’t be more needed trauma n stress anxiety’s my middle name can’t believe im still here

  3. @LoriMcalroy

    September 23, 2025 at 11:07 am

    I was thinking this yesterday when it came to ibs and gastrics problems

  4. @Leto2ndAtreides

    September 23, 2025 at 12:09 pm

    What drug did you use for your Castleman disease?

  5. @TheBestLifeMindsetWithShelly

    September 23, 2025 at 1:24 pm

    Inspiring conversation! I love the focus on turning hope into concrete action, such a powerful reminder that small, consistent steps create real change. 💖

  6. @claires9100

    September 23, 2025 at 1:27 pm

    Holding despair and hope together is a very powerful concept. Hope in action is so important. This really resonates with me .

  7. @MaiAnnChan

    September 23, 2025 at 2:58 pm

    Truly inspiring story,just what my nephew is doing in Toronto, Canada, smart man❤❤❤❤❤

  8. @MaiAnnChan

    September 23, 2025 at 2:59 pm

    Great for those who are able to give their own TED talk❤❤❤❤😊🎉🎉❤❤

  9. @innerrise.official

    September 23, 2025 at 7:58 pm

    It’s truly inspiring to hear how two incredible individuals are turning hope into tangible action, tackling massive challenges in healthcare and social systems.

  10. @todaycountsshow

    September 24, 2025 at 4:39 am

    Holding hope and despair together fuels resilience, purpose, and meaningful impact. 🌱

  11. @KkKk-t2c7d

    September 24, 2025 at 6:30 am

    My friend, I find that formal British English, like what we hear on the BBC, is clear and beautiful. But I also understand that it’s important to learn both formal and casual English at the same time.

    The challenge is that British casual English feels very difficult for me, and there are so many different regional accents.

    So my question is: would it be acceptable to focus on formal British English, while also learning American casual English? I feel that American casual English is much easier to follow than British casual English.!

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Jermaine Dupri on the Art of Making a Hit | On the Spot | TED

Legendary music producer Jermaine Dupri pulls back the curtain on how hit songs really get made in TED’s rapid-fire Q&A format, “On the Spot.” Answering a stream of unexpected questions, he covers what makes a good hook, why he doesn’t chase “cool,” how he helped build Atlanta’s sound and more. (Recorded at TEDNext 2025 on…

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Legendary music producer Jermaine Dupri pulls back the curtain on how hit songs really get made in TED’s rapid-fire Q&A format, “On the Spot.” Answering a stream of unexpected questions, he covers what makes a good hook, why he doesn’t chase “cool,” how he helped build Atlanta’s sound and more. (Recorded at TEDNext 2025 on November 10, 2025)

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The TED Talks channel features talks, performances and original series from the world’s leading thinkers and doers. Subscribe to our channel for videos on Technology, Entertainment and Design — plus science, business, global issues, the arts and more. Visit to get our entire library of TED Talks, transcripts, translations, personalized talk recommendations and more.

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TED’s videos may be used for non-commercial purposes under a Creative Commons License, Attribution–Non Commercial–No Derivatives (or the CC BY – NC – ND 4.0 International) and in accordance with our TED Talks Usage Policy: . For more information on using TED for commercial purposes (e.g. employee learning, in a film or online course), please submit a Media Request at

#TED #TEDTalks #OnTheSpot

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Boys experience more violence when they’re young than you think. Here’s how things change #TEDTalks

Urging us to turn away from voices perpetuating harmful stereotypes, gender equality advocate Gary Barker shares three insights on fostering a culture of care, compassion and connection among men. “We are the most wired-to-care species on the planet,” he says. “But if you don’t use it … you don’t get good at it.”

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Urging us to turn away from voices perpetuating harmful stereotypes, gender equality advocate Gary Barker shares three insights on fostering a culture of care, compassion and connection among men. “We are the most wired-to-care species on the planet,” he says. “But if you don’t use it … you don’t get good at it.”

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The New Science of Eyewitness Memory | John Wixted | TED

We’ve built a legal system that distrusts eyewitness memory — backed by cautionary science and high-profile exonerations. John Wixted, a leading psychology researcher, challenges this conventional wisdom with a counterintuitive finding: the problem might not be memory itself but how (and when) courts test it. (Recorded at TEDxUCSanDiego on May 17, 2025) Join us in…

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We’ve built a legal system that distrusts eyewitness memory — backed by cautionary science and high-profile exonerations. John Wixted, a leading psychology researcher, challenges this conventional wisdom with a counterintuitive finding: the problem might not be memory itself but how (and when) courts test it. (Recorded at TEDxUCSanDiego on May 17, 2025)

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Become a TED Member to support our mission:
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The TED Talks channel features talks, performances and original series from the world’s leading thinkers and doers. Subscribe to our channel for videos on Technology, Entertainment and Design — plus science, business, global issues, the arts and more. Visit to get our entire library of TED Talks, transcripts, translations, personalized talk recommendations and more.

Watch more:

TED’s videos may be used for non-commercial purposes under a Creative Commons License, Attribution–Non Commercial–No Derivatives (or the CC BY – NC – ND 4.0 International) and in accordance with our TED Talks Usage Policy: . For more information on using TED for commercial purposes (e.g. employee learning, in a film or online course), please submit a Media Request at

#TED #TEDTalks #Memory

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