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How Ibogaine Could Treat Depression and Anxiety | Nolan Williams | TED

The late Stanford neuroscientist Nolan Williams shares his research on the potential of a plant-derived psychoactive compound called ibogaine to help people with traumatic brain injury recover from PTSD, depression and anxiety. (Followed by a brief Q&A with Head of TED Chris Anderson)(Recorded at TED2025 on April 10, 2025) Join us in person at a…

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The late Stanford neuroscientist Nolan Williams shares his research on the potential of a plant-derived psychoactive compound called ibogaine to help people with traumatic brain injury recover from PTSD, depression and anxiety. (Followed by a brief Q&A with Head of TED Chris Anderson)(Recorded at TED2025 on April 10, 2025)

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36 Comments

36 Comments

  1. @i.spoiderman

    January 12, 2026 at 11:01 am

    First commenter

  2. @ANYTHING-zt8fk

    January 12, 2026 at 11:02 am

    2nd commenter

  3. @AG-yc4lz

    January 12, 2026 at 11:07 am

    I thought this was Dax Flame-_-

  4. @mariansmith7694

    January 12, 2026 at 11:16 am

    It is all about money. Pharmaceutical industry is ABSOLUTELY EVIL. For most part AMA is same.

    • @Amygdala1992

      January 12, 2026 at 12:00 pm

      I have anxiety disorder please tell me can this help

    • @liquidbraino

      January 12, 2026 at 7:35 pm

      ​@Amygdala1992Try Kundalini Yoga. Try hemi-sych technology. Also be very careful with your diet and sleep cycles. And be careful with what you ALLOW yourself to focus on repetitively. Your focus determines your reality which is why it helps to learn meditation, Nei Gung, Tai Chi, Kundalini Yoga etc. What works for me might not work for you though – try ALL of them and figure out which ones work best for you. Look into Dr Robert Beck and his Brain Tuner machine also – he gave a lecture in 1983 that you can find on YouTube. Find it – listen to it. Get out into nature as often as you can; walk barefoot on grass as often as you can.

      Don’t trust the FDA or pharmaceutical companies. The FDA approves big pharma drugs which kill 2,000 people per year BECAUSE 60% of all FDA officials own stock in the companies that they’re supposed to be regulating.

  5. @Ikrell-Laires

    January 12, 2026 at 11:25 am

    Big Pharma can not make money off happy , healthy humans

  6. @kevinl4966

    January 12, 2026 at 11:27 am

    Thank you…… .

  7. @dilirix-dei

    January 12, 2026 at 12:12 pm

    In this context, psychologists and psychiatrists are anti-fruiters, because they will be left without work. They tried so hard to create DSM-5 to have more clients) So they will not give up so easily and will put spokes in the wheels of new developments that really treat, and not just pump money out of naїve clients year after year.

    • @AustinCS

      January 12, 2026 at 6:08 pm

      The fist version of DSM even had in it that it wasn’t a hard and fast rulebook, but the brain disease model changed the way it was used and how much it was treated as a source of truth. I agree that it’s leaned on too heavily, and the politics involved have led to the rejection of Developmental Trauma Disorder by the APA. Cookbook psychiatry makes insurance more money!

  8. @darinrmcclure

    January 12, 2026 at 12:50 pm

    Genesis 1.29 🙏

    • @TinCents

      January 15, 2026 at 6:38 am

      “And God said, ‘Behold, I have given you every plant yielding seed that is on the face of all the earth, and every tree with seed in its fruit. You shall have them for food.’”

  9. @thatcheechmami

    January 12, 2026 at 1:15 pm

    RIP Dr. Nolan Williams. Thank you for your contributions to field of psychiatry and neuroscience, and for your immense dedication to studying break through mental health treatments for depression and anxiety. Your work mattered; you mattered.

    • @hansolowe19

      January 15, 2026 at 6:52 pm

      Did he not try it? 😔

  10. @MrLoobu

    January 12, 2026 at 2:10 pm

    There are a lot of drugs that can really help anxiety or depression permanently from one use. Most are illegal.

    • @liquidbraino

      January 12, 2026 at 7:27 pm

      Thank the FDA for that. 60% of all FDA officials own stock in the companies that they’re supposed to be regulating and they spend millions each year to shut down the competition. If they can’t make money from it they’ll shut it down – just like they did to Dr Robert Beck with his “Brain Tuner” machine and Dr Margaret Patterson with her “Meg Net” machine that cured several different rock stars of their drug and alcohol addictions. The FDA can’t make money by selling 9v batteries but they can make money by getting people addicted to Methadone which is even more addictive than heroin – it is not a “solution”. The FDA is nothing but a legalized drug cartel.

  11. @gabrielramos5790

    January 12, 2026 at 6:38 pm

    I can give a kid an orange, can I give a kid that compound?

    • @MetalHeadSippel

      January 12, 2026 at 9:22 pm

      Absolutely not. The reason being the brain is not fully formed until the age of 25, so even with all the positive aspects of natural medicine, ie marijuana, psilocybin mushrooms, and Ibogaine, these compounds can negatively effect the developing brain before adulthood.

  12. @DistortedV12

    January 13, 2026 at 1:11 am

    RIP man.. ibogaine may not help, but your efforts will be remembered

  13. @drinkapavlovic

    January 13, 2026 at 1:45 am

    I couldn’t believe my own ears when I heard that Professor Nolan Williams had passed away. I suffer from depression, and I feel completely lost right now. I feel so sorry for him.

    • @Renateneetje

      January 13, 2026 at 3:42 am

      🙏

    • @AustinMooney-b4d

      January 14, 2026 at 11:51 am

      Don’t feel bad for the dead they don’t feel anything just a joke mental health is an important part of life

    • @hansolowe19

      January 15, 2026 at 4:33 pm

      You are loved. 🫂

  14. @catalinanazal1595

    January 13, 2026 at 2:23 am

    We need this for every single veteran, for every survivor of abuse, please watch the documentary about it In Waves and War

  15. @DaleWoodward-v7z

    January 13, 2026 at 5:25 am

    That’s interesting. I’ve been treating a domesticated former stray cat for the last 4 years, rescued at the age of ~ 1 year, turned out she had PTSD from starving and almost being killed by dogs in our neighborhood. I did research over what I could give her to help calm her down and came across ashwagandha drops, which work really well, as they also got her cortisol levels managed, and now she’s a healthy, ~ 18 pound semi-feral cat. 2 drops a day of the stuff, one in her food in the AM, one in the PM, and she’s a healthy happy kitty.

  16. @angeluslogus

    January 13, 2026 at 6:17 am

    In the “land of freedom”, you only don’t have freedom of consciousness and from big pharma…

  17. @alexrice2302

    January 13, 2026 at 7:43 am

    The schedule 1 status of a drug means: “no medicinal value” and yet heroine is prescribed, it’s called diamorphine. Cannabis is prescribed, it’s called marinol…. I think schedule 1 means the drug companies can’t control or profit from it.😊

  18. @saml8119

    January 13, 2026 at 11:57 am

    Really hope this makes it through trials and becomes a legal option. Would be nice to see it become a more available option soon

  19. @cheebacheeo

    January 13, 2026 at 4:15 pm

    I did Ibogaine trip 2018, and it was a game changer for me. Depression gone, quit smoking, drinking, done with meaningless relationships, stopped shoplifting etc, etc. But ibogaine only showed the way, I did the work. It was effortless tho.

    • @rulasartandbooks

      January 14, 2026 at 6:47 am

      How can I get Ibogaine?

  20. @TiffinBigD

    January 14, 2026 at 2:12 pm

    👁️⚡️ Psychedelics are the answer big pharma doesn’t want to prescribe because they actually work, often in one dose

    • @Pete-s5g8o

      January 15, 2026 at 12:07 am

      Psychedelics are definitely a threat to the proprietary business model of healthcare and pharma. The science is inspiring, yet is not covered or promoted as it would be in competition with a big money maker, SSRIs and non-generic medicines. Living with a TBI, I struggle to learn more about neuroscience and methods of recovery from treatment refractory depression. Sadly, what I am learning does not work within the business model of healthcare that says if it can’t be diagnosed and reimbursed, it doesn’t exist. For 38 years I worked as a healthcare professional, until an assault ended my nursing career and left me with a severe TBI. Having seen the big pharma and healthcare approaches and having suffered from life threatening conditions while searching for hope, I didn’t know how limiting medical models and restrictions were until it was personal to me.

  21. @jasminha9785

    January 14, 2026 at 5:41 pm

    Oranges are safer than Ibogaine by far so not really a fair comparison. I’m in favor of psychedelics for healing.

  22. @jannetteberends8730

    January 15, 2026 at 1:34 pm

    And all the time those people died of scurvy, German and Dutch ships took sauerkraut with them on their journeys, and stayed healthy.

  23. @MrMoonFlame

    January 15, 2026 at 4:13 pm

    Odd that this was withheld until after his untimely death

  24. @Yourenotreal7

    January 15, 2026 at 8:00 pm

    How awful… rest in peace… deep thinkers and brilliant people🫶

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