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The Human Cell Is Wildly Complex. Can AI Decode It? | Silvana Konermann | TED

Silvana Konermann and the team at Arc Institute are trying to crack one of science’s most difficult problems: why complex diseases like Alzheimer’s and cancer remain so stubbornly unsolvable, even as research advances. Her solution is a universal “virtual cell” — an AI model trained on a billion biological experiments that can read the language…

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Silvana Konermann and the team at Arc Institute are trying to crack one of science’s most difficult problems: why complex diseases like Alzheimer’s and cancer remain so stubbornly unsolvable, even as research advances. Her solution is a universal “virtual cell” — an AI model trained on a billion biological experiments that can read the language of human cells, predict what’s going wrong and reveal how to fix it. In conversation with TED’s Chris Anderson, Konermann explores how this work could fundamentally change the way we discover drugs and treat disease. (This ambitious idea is part of The Audacious Project, TED’s initiative to inspire and fund global change.) (Recorded at TED2026 on April 14, 2026)

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23 Comments

23 Comments

  1. @Unreality_Rooms

    June 19, 2026 at 11:11 am

    see you in a decade…
    see you in a decade if there will be a decade…
    I bet humans will still be relevant if I see you in a decade…
    let time prove these statements…and if YouTube will still exist…

    • @haiku-u6t

      June 19, 2026 at 12:13 pm

      Dude that ‘learned to code’ thinking that he was beyond replacement. I’m a musician and even I know the AI does a better job in most cases.

    • @RamaDevi-mu6of

      June 19, 2026 at 3:49 pm

      Thanq for the wonderful info .Without human mind prompts AI couldnt perform …for sure. There is a beautiful collaborative work between Human mind n AI. In this process there will be exchange of thoughts by the gravity of humans. Full of magical happenings….on this Earth’s gravity. Prayers.rd

  2. @jaydensmith920

    June 19, 2026 at 11:26 am

    Maybe we dont let computers do this one?

    • @haiku-u6t

      June 19, 2026 at 12:11 pm

      @jaydensmith920 why? It’ll identify people that are susceptible to genetic illness and allow them access to treatment before a disease develops?

    • @ee3171

      June 19, 2026 at 12:48 pm

      This is already applied in Bioinformatics, one of the important fields in modern medicine, try reading a book on it?

    • @ritamsadhukhan772

      June 19, 2026 at 1:38 pm

      Are you kidding me ? Biology is fucking complex AI is the only bloody tool humans have to do this bro why bro why

  3. @user-kq2tc5hy5g

    June 19, 2026 at 11:27 am

    confusing how actual scientist are typically modest in manners and appearance, in contrast to some “science communicators” getting into a contest for skin-revelation, make-up and fashion instead of focusing on the actual science matter at hand.

  4. @CRECEMYFILHOVE

    June 19, 2026 at 11:37 am

    I really appreciate content like this, I think that more people should promote content like this that helps and encourages people with topics of global interest.

  5. @umangchhatrola7223

    June 19, 2026 at 12:41 pm

    Nature cure practitioners already have an answer to these questions. Can we allow and promote scientific studies where the solution can’t be monetised?

    The food is already there: just not in the plate that the modern medicine loves.

    • @ee3171

      June 19, 2026 at 12:46 pm

      ​@umangchhatrola7223 Lmao “Nature cure” is the pot calling the kettle black here.

    • @verderriscursey

      June 19, 2026 at 12:52 pm

      @ee3171 how you figure that? Natural cures dont cost an arm and a leg and instead of big pharma telling, hey we synthesized this med from this plant so if you cant afford ours heres the alternative. Big pharma should be required to disclose this info

    • @verderriscursey

      June 19, 2026 at 12:54 pm

      The FDA allowing inflammatory foods and chemicals into the supply is the main problem…food and drug admin equals profits for big pharma

  6. @DougVarble

    June 19, 2026 at 12:54 pm

    17:01 GREAT contact🎉

  7. @seemajoshi9880

    June 19, 2026 at 2:05 pm

    Phenotype is environment dependent. it would be amazing if LLMs can capture environment dependence from RNA signals.

  8. @Tooltilities

    June 19, 2026 at 3:17 pm

    what a brilliant concept. id heard ai was helping in other fields, but first time ive heard it explained like this. well done with your first public appearance. very well presented.

  9. @ThinkingBetter

    June 19, 2026 at 3:29 pm

    AI will figure out everything concerning how cells work and also eventually how abiogenesis could happen. Eventually AI will create a model for everything that explains our universe down to how intelligent life came out of it.

  10. @worldbrotherhoodglobal

    June 19, 2026 at 4:24 pm

    We build everything around fast profits and efficiency, then wonder why modern life feels so repetitive and empty. We need to start building for actual humans again.

  11. @ישראלגוטליב-ג4מ

    June 19, 2026 at 4:53 pm

    As a human race, we need more people like her—humble, generous, and concerned for the common good.

  12. @crawkn

    June 19, 2026 at 6:05 pm

    This is a potentially world-changing advancement, but I worry that with healthcare being unaffordable in many nations, its benefits may not be fairly distributed.

  13. @think32

    June 19, 2026 at 7:54 pm

    I’m often in conversations with others demonizing AI. Personally, I find the technology incredibly fascinating and powerful. Whether it is destructive or beneficial hinges on its use-case, which is determined by the passions and integrity of those putting it to use. I’m so happy to see examples of humanity-motivated uses, rather than profit-driven uses. Thanks, TED!

  14. @RockyMtnThai

    June 19, 2026 at 8:55 pm

    I use AI as a research partner. I posit and it provides the high level math and physics, I provide the theroeries it provide the math. If physics is logic based, then anyone with a clear, lucid, analytical mind can drive it. This research is breaking new ground.
    For example, in my GUT, I hypothesize that DNA is more that it appears. I posit that it actually acts as a PDF (Portable Document file). Only 2% of DNA generates proteins. Science considers the remaining 98% as junk. This is a ludicrous “Assumption” that cannot possibly be true.
    Traditional science should be very concerned. Myself and other “Hobby Physystics” are forging new ground and actually realizing groundbreaking/transformative results. Modern Physics has produced no new paradigm breaking discoveries in 50 years. They refuse to accept they are on the wrong path and repeatedly output their tortured math and twisted analogies, trying to make the universe conform to it’s myopic view. But, as the say, “Science advances, one funeral at a time”.

  15. @saranbhatia8809

    June 19, 2026 at 9:12 pm

    Great talk great information!!

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Science & Technology

Is There an AI Bubble? Two Top VCs on Valuations and ARR Inflation | StrictlyVC LA 2026

Is AI venture capital in a bubble, or are we just in the steepest growth curve anyone’s ever seen? At StrictlyVC Los Angeles 2026, TechCrunch’s Editor-in-Chief Connie Loizos sat down with Chung Xu, Partner at Basis Set, and Carter Reum, co-founder of M13, to cut through the noise. They cover… – Why this cycle is…

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Is AI venture capital in a bubble, or are we just in the steepest growth curve anyone’s ever seen?

At StrictlyVC Los Angeles 2026, TechCrunch’s Editor-in-Chief Connie Loizos sat down with Chung Xu, Partner at Basis Set, and Carter Reum, co-founder of M13, to cut through the noise. They cover…

– Why this cycle is different from cloud and mobile, and why it isn’t
– The ARR inflation problem VCs helped create
– How to find defensible companies when OpenAI and Anthropic are coming for every vertical
– What the SpaceX liquidity wave means for LA’s tech ecosystem

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He Dropped Out of MIT at 19 to Build America’s Drone Arsenal. It’s Working | StrictlyVC LA 2026

Ethan Thornton started Mach Industries at 16, dropped out of MIT, and is now running six simultaneous defense programs: jet engines, cruise missiles, a surface-to-air missile system, and a new 40-foot VTOL strike aircraft just contracted by the U.S. Navy. At StrictlyVC Los Angeles 2026, TechCrunch Editor in Chief Connie Loizos sat down with the…

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Ethan Thornton started Mach Industries at 16, dropped out of MIT, and is now running six simultaneous defense programs: jet engines, cruise missiles, a surface-to-air missile system, and a new 40-foot VTOL strike aircraft just contracted by the U.S. Navy.

At StrictlyVC Los Angeles 2026, TechCrunch Editor in Chief Connie Loizos sat down with the Mach Industries founder and CEO for a rare on-stage conversation about what it actually takes to build a serious defense hardware company from scratch — and why the U.S. has no choice but to move faster.

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90% of “American” Fish Gets Processed in China. This Startup Is Changing That | StrictlyVC LA 2026

More than 90 percent of American-caught fish is processed overseas, and often in China, before it comes back to the U.S. Shin K wants to change that with robotics, computer vision, and a vertically integrated supply chain built from scratch. At StrictlyVC Los Angeles 2026, TechCrunch Editor in Chief Connie Loizos sat down with Saif…

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More than 90 percent of American-caught fish is processed overseas, and often in China, before it comes back to the U.S. Shin K wants to change that with robotics, computer vision, and a vertically integrated supply chain built from scratch.

At StrictlyVC Los Angeles 2026, TechCrunch Editor in Chief Connie Loizos sat down with Saif Khawaja, founder and CEO of Shin K, and Delian Asparouhov of Founders Fund to talk about one of the most unexpected bets in venture capital right now.

They cover everything from the Japanese fish-killing technique that became a startup thesis, why American fish is now being imported into Japanese fish markets for the first time ever, and how Founders Fund thinks about contrarian bets in food and agriculture.

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