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A new class of drug that could prevent depression and PTSD | Rebecca Brachman

Current treatments for depression and PTSD only suppress symptoms, if they work at all. What if we could prevent these diseases from developing altogether? Neuroscientist and TED Fellow Rebecca Brachman shares the story of her team’s accidental discovery of a new class of drug that, for the first time ever, could prevent the negative effects…

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Current treatments for depression and PTSD only suppress symptoms, if they work at all. What if we could prevent these diseases from developing altogether? Neuroscientist and TED Fellow Rebecca Brachman shares the story of her team’s accidental discovery of a new class of drug that, for the first time ever, could prevent the negative effects of stress — and boost a person’s ability to recover and grow. Learn how these resilience-enhancing drugs could change the way we treat mental illness.

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The TED Talks channel features the best talks and performances from the TED Conference, where the world’s leading thinkers and doers give the talk of their lives in 18 minutes (or less). Look for talks on Technology, Entertainment and Design — plus science, business, global issues, the arts and more.

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51 Comments

51 Comments

  1. Avatar

    En ki

    April 18, 2019 at 12:12 am

    I think this is worldwide commercial for Ketamine!!!
    The new wonder drug, where everyone r stress free (cyborgs or terminators)!!!
    Let’s ignore where the problems come and just drink pills!
    Let’s the richer get even more rich and poorer become rats!

  2. Avatar

    TRILLION CROWNS

    April 18, 2019 at 12:13 am

    GRASS!!!!!!!

  3. Avatar

    humanoid

    April 18, 2019 at 12:23 am

    Another rehearsed memorized speech given by a pharmaceutical human robot

  4. Avatar

    TenaciousC

    April 18, 2019 at 12:27 am

    I know, I know. Keep an open mind.

  5. Avatar

    Anotherthez

    April 18, 2019 at 12:28 am

    It won’t treat you, only prolong your zombieness; that’s not living…!

  6. Avatar

    Sergey MATPOC

    April 18, 2019 at 12:37 am

    Oh, I need one. Right now I’m in 6 weeks after move to USA, being interviewed a lot with major companies for high-rank positions in a non-native language, that’s much harder too. So I have a really strong emotional pressure and that cure would help people like me and other ones to bear such processes easier and much more calm. There won’t be such statistics as we have now, like, half of families divorce after immigration. If people could recover from stressful situation much faster – they won’t get in such hard situations in future, will preserve families and eventually will move world forward quicker, because immigrants would feel more comfortable in “hostile” unknown environment and will naturalize very efficiently and quick.
    If the question is about do I need such pills in my world – my answer is only Yes. There is no other ethic point of view for me.

  7. Avatar

    Analogy Accepted

    April 18, 2019 at 12:55 am

    Yes, more drugs, that’s the ticket! Are they addictive, too? Then it’s *really* the ticket for US.

  8. Avatar

    Seth okthen

    April 18, 2019 at 1:00 am

    When people become aware of the hazards of current medicines, whats the solution? Create new drugs that no ones ever heard of. LOL. There is no magic cure for anything, its all hard work and people. Exercise, diet, being in the real world, making real friends instead of stupid virtual ones, are easily the best ways to enhance quality of life.

  9. Avatar

    kerpele

    April 18, 2019 at 1:09 am

    Clown world

  10. Avatar

    U W U

    April 18, 2019 at 1:25 am

    I wish I could have taken some of those pills before diving into the comments.

  11. Avatar

    Amanda Anderson

    April 18, 2019 at 1:31 am

    You are not going to prevent traumatic situations and there is no way to know when it will happen except in willingly marching to war.
    On another note this is a good idea for soldiers bit needs to be paired with rehabilitation therapy and reintegration therapy.

  12. Avatar

    Anonymous User

    April 18, 2019 at 1:35 am

    What kind of fool thinks the depression problem is solved with a new drug?
    Too many smart people (or people with degrees..) with 0 common sense / self knowledge

  13. Avatar

    Ayra

    April 18, 2019 at 1:40 am

    I didn’t know TED talks do sales pitch now

  14. Avatar

    greentealatte

    April 18, 2019 at 1:56 am

    That new drug is called NOT OVERTHINKING

  15. Avatar

    Michael Starlight

    April 18, 2019 at 1:58 am

    I had depression and the doctor’s kept prescribing me psychotropic anti-depressants that did not work it wasn’t until by chance I was prescribed this new medication called Nuvigil and it actually cure my depression and increase my IQ by 30% true story!

  16. Avatar

    Pretty Prudent

    April 18, 2019 at 2:01 am

    Instead of another “drug”, why not just pursue an all-meat diet – or water fasting (don’t forget the salt). It’s worked for many.

  17. Avatar

    Lee Charles Prochazka

    April 18, 2019 at 2:27 am

    Best of Ted talk

  18. Avatar

    Jaider Nunes

    April 18, 2019 at 2:30 am

    Damn.. I cant believe this is on ted. Disgusting

  19. Avatar

    Andrea Guardascione

    April 18, 2019 at 2:42 am

    there are A LOT of natural way to move out of depression and PTSD, pushing drugs for that is insane. Check hypnotherapy, EFT, EMDR etc etc etc

  20. Avatar

    Steve Borkowski

    April 18, 2019 at 2:54 am

    Bullshit! Stop looking for a DRUG solution!!!

  21. Avatar

    J R

    April 18, 2019 at 3:13 am

    Ketamine?
    If yes, Why did she say it was ‘a new class of drugs’ K is an Arylcyclohexylamine which is not new. ?

  22. Avatar

    Muratov North

    April 18, 2019 at 3:14 am

    All the drugs have a side effect so we’ll just see. Moreover, in order to be immune to them will take us generations.

  23. Avatar

    Alisa B

    April 18, 2019 at 3:17 am

    Would these drugs be addictive as well?

  24. Avatar

    Ryan Lanc

    April 18, 2019 at 3:21 am

    Didn’t they do that in Serenity? Whatever, I hope it’s the start of the zombie apocalypse. I’m pretty sure I could take on the reivers.

  25. Avatar

    Alex Korban

    April 18, 2019 at 3:28 am

    Надеюсь будет перевод в субтитрах.

  26. Avatar

    David Waelder

    April 18, 2019 at 10:41 pm

    Not specific at all. Feels like commercial from a robot.

  27. Avatar

    Football Explained

    April 19, 2019 at 12:35 am

    Lol pharmaceutical drugs are the drugs that harm us Americans.

  28. Avatar

    Cobi O'Brien

    April 19, 2019 at 2:44 am

    THE DRUGS THAT FIX DEPRESSION AND ANXIETY ARE ILLEGAL. MUSHROOMS. LSD. DMT. WAKE UP

    • Avatar

      Bird Bird

      April 19, 2019 at 3:27 am

      Don’t fucking tell me what I can and can’t take. Don’t tell me what I can and can’t eat. Don’t tell me what is and what isn’t good for me. America’s not as good as WE SAID and SAY it is…

  29. Avatar

    Bird Bird

    April 19, 2019 at 3:29 am

    “Deppression is triggered mainly by stress”
    Hahahaha that’s funny because America’s school system is doing a good job at that! You won’t believe the amount of people that cut and don’t show up anymore…

  30. Avatar

    olio

    April 19, 2019 at 5:17 am

    This is a sales pitch more than a scientific presentation. What does the graph @ 2:22 onward represents? what is sec/min? what is being measured? Not one hint on how this works. It looks to me like a presentation for collecting funds and investment.
    You torture a small innocent mouse for three weeks be injecting the poor thing with stress hormones while you enjoy your day and get a good night sleep, and then come to brag about it! have you any conscious at all?

  31. Avatar

    Joan Tron

    April 19, 2019 at 9:42 am

    Tylenol is one of the few drugs that were commonly given to pregnant women. Come to find out Tylenol decreases empathy and testosterone. Big Pharma are thieves, cheats and scum psychopaths. Don’t forget that when you take their drugs. They really are not to be trusted.

  32. Avatar

    cgfreeandeasy

    April 19, 2019 at 10:20 am

    Its not “exactly” Ketamin, but substance-class.
    And it works in intention by mikrodose-application. And it doeas not make “happy”, but uncritical against ambient conditions, so that the subject does not identify himself with reality around him.

    Thats, what in other context (Drug-abuse) meaned, when said, that they become careless, halfhearted, indifferent, insensible, superficial …etc

    It should therefore be explained why, in view of this objective (stressor prevention, prevention of stress effects), all the earlier views on drug use and its consequences should now be acceptable side effects, where they were previously always cited as the main drawbacks.

    What happens with this medication is in fact the opposite of what one used to demand of all people: to be aware of oneself and one’s environment and one’s own actions, to be responsible and attentive, to be “on the ball”, and to “think the situation through”.

    In the thesis of stress prevention with this substance class, however, exactly the opposite is produced.

    But if one assumes that man, because he is a small wheel in the wheels of life and in the universe, should not take the whole thing around him so seriously, then exactly this is the right strategy: governmental/structurally legalized will-less making through creeping ketamine intoxication.

    Does anyone remember the film “Equilibrium”?

    Translated with http://www.DeepL.com/Translator

  33. Avatar

    RtrNi

    April 19, 2019 at 10:22 am

    It’s ketamine

  34. Avatar

    Sunil S

    April 19, 2019 at 11:10 am

    What a shame, at first place we make people depressed by our act, then again chemically abuse them in the name of treatment!!!!

  35. Avatar

    Susanna D

    April 19, 2019 at 1:41 pm

    Stress resilience drugs……??‍♀️what a crock

  36. Avatar

    Delwar Hossain

    April 19, 2019 at 2:25 pm

    Beautiful nice girl..

  37. Avatar

    sometimes 1008

    April 19, 2019 at 3:29 pm

    I completely disagree. The only solution to depression is to realize that your emotional state is 100% your making. Either take the reigns conciously or let outside forces control you, it takes focus, but it is a choice. I was suicidally depressed for years and undergone doctors treatment as well as my own.. trust me, there are NO kind of drugs that are a permanent solution.

  38. Avatar

    Axel Werner

    April 19, 2019 at 6:53 pm

    I bet this new drug also cures cancer AND solves the worlds hunger too. And it can make you live 100 years longer if you buy it on a daily basis, i have heard. Its a wonder elixir.

  39. Avatar

    Paul Fagan

    April 19, 2019 at 7:13 pm

    So whats this magic substance how does it chemically work? is she announcing this because she wants to secure a patent with big |Pharma ?????

  40. Avatar

    Abhay Bhatt

    April 19, 2019 at 7:56 pm

    She could easily get work in Hollywood, in fact, she closely resembles a Hollywood/Bollywood actress.

  41. Avatar

    Jmad0113

    April 19, 2019 at 9:21 pm

    Yes definately, I think in the long run both enhance each other. So the effectiveness of either one improves as each of the two options are done

  42. Avatar

    Jmad0113

    April 19, 2019 at 9:22 pm

    So the root cause is complicated, cause as much as I wanted to change my internal feelings/thoughts, my diet/medicine had to be changed for even to start taking effects.

  43. Avatar

    mmisbach

    April 19, 2019 at 11:28 pm

    Many professions increase risk of depression & PTSD (military, medical, etc), most treatments simply suppress symptoms. A new class of drug called a resilience enhancer reduces side-affects to stressors. #TedTalk

  44. Avatar

    Boss Lax316

    April 20, 2019 at 12:37 am

    But this is all hypothetical as it hasn’t yet been tested on humans

  45. Avatar

    UDtheAesir

    April 20, 2019 at 1:39 am

    Gotta have psychedelics for PTSD and depression! DMT, cannabis, shrooms and LSD are your best friends.

  46. Avatar

    nasry nordyn

    April 20, 2019 at 2:24 am

    keyword = could
    big pharma companies only know to make profit

  47. Avatar

    1Dollar Munkytrix

    April 20, 2019 at 5:22 am

    Great, let’s just be customers on drugs our whole lives just in case we ever get stressed. Who needs to develop coping/ reality skills?
    Wim Hoff disproves this entire lecture, just saying…

  48. Avatar

    TORONTO CANADA

    April 20, 2019 at 6:49 am

    It’s called sunshine, exercise and eating well.

  49. Avatar

    sunnyuliya

    April 20, 2019 at 3:06 pm

    Ketamine pushers are getting creative.

  50. Avatar

    barry weber

    April 20, 2019 at 7:43 pm

    Did not explain why Soldiers that have PTSD and are allowed to have a gun in a home.

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