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What If You Could Read the DNA of Your Future Child? | Noor Siddiqui | TED

For all of human history, a baby’s DNA was determined by chance at conception: the so-called genetic lottery. “That era is over,” says Noor Siddiqui, whose company builds screening tools to read the whole genome of embryos in an effort to give parents more genetic information than standard IVF. She makes the case that this…

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For all of human history, a baby’s DNA was determined by chance at conception: the so-called genetic lottery. “That era is over,” says Noor Siddiqui, whose company builds screening tools to read the whole genome of embryos in an effort to give parents more genetic information than standard IVF. She makes the case that this kind of technology helps families understand and reduce health risks, raising the question: How much should we know about our children’s DNA before birth? (Followed by a brief Q&A with TED’s vision steward Sal Khan) (Recorded at TED2026 on April 15, 2026)

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32 Comments

32 Comments

  1. @Ccrits3

    October 29, 2026 at 11:37 am

    On some level I understand not wanting to have babies that have genetic conditions that make it so they don’t even live to the 1st birthday. However, this is baseline eugenics. Mental disorders and physical disabilities are things people learn to navigate the world through.

    These are not all things to be bred out of society, and the end towards selective breeding to yield a population with enhanced color spectrum visibility, bones, endurance is still eugenics.

    I understand this lady had a mom that lost her sight due to a genetic disorder. However, it is quite faulty to advocate for this for others. Also, does she really think it’s going to be affordable for everyone when people can’t even afford basic necessities and people are homeless and dying from preventable causes?

    I envision a future where, as the wealth divide grows, the elite are the ones who have access to such intricate forms of genetic selection that they are superhuman compared to the rest of the populace. This is a very slippery slope and I truly think it should be outlawed.

    • @lisastratton3869

      October 29, 2026 at 12:48 pm

      To your point about the speaker’s mom, my thought is this isn’t a practice the eliminates mom’s experience with blindness…it’s a practice that eliminates mom…and her descendants. The speaker would not exist if grandma had rejected an embryo due to eventual genetic blindness. I still think I’d be uncomfy if we were talking about genetic modifications…I don’t think I’d be who I am without my neurodevelopmental conditions personally, but this is genetic selection as in this one characteristic means a potential person is not allowed to exist. So even the mention of what if mom didn’t have to go blind…it’s very confusing how this is presented with so much enthusiasm.

    • @BonnieShadow33

      October 29, 2026 at 7:26 pm

      ​@lisastratton3869 Agreed!!

  2. @robbinanncoronado8610

    October 29, 2026 at 11:42 am

    😂😂😂😂 0:16

  3. @lisastratton3869

    October 29, 2026 at 11:46 am

    This is horrific to me. I have some of the conditions listed as now screenable at conception, and I am a whole person who creates value with my life, and I am a legal guardian of a disabled adult who also has some of these conditions and who is also a precious gift to humanity. For terminal conditions, I suppose this is a reasonable practice. For anything else, I can’t help but be horrified. And it’s trippy to me to hear this presented so positively.

  4. @thebuffalo2263

    October 29, 2026 at 11:51 am

    Before all the religious clowns start in the comments just remember all religion is man made fiction. Grow up

    • @Maxipadtriplesix

      October 29, 2026 at 12:05 pm

      This is eugenics. You want to advocate for eugenics?

    • @thebuffalo2263

      October 29, 2026 at 1:50 pm

      @MaxipadtriplesixI want to eliminate pain and suffering of parents and children while promoting healthy births. Grow up. You eat food that genetically modified. We have the technology to do it, why do you get to tell people what to do? Grow up!

    • @Maxipadtriplesix

      October 29, 2026 at 2:57 pm

      @thebuffalo2263Lmao how often you say grow up indicates how young you are.

    • @thebuffalo2263

      October 29, 2026 at 3:23 pm

      @MaxipadtriplesixYou didn’t respond to the last comment because you know you are wrong. You insulted me. As I stated before, GROW UP!

  5. @Maxipadtriplesix

    October 29, 2026 at 12:03 pm

    Not hatin on the ladies, but we all know there would be some sort of trendy instagram or tik tok gene-build for a baby that most ladies would choose to implement on their kids because it’s the trend.
    This idea is horrible though, why are we trying to rebrand eugenics?

  6. @VindicatorsPledge

    October 29, 2026 at 12:06 pm

    Partner has Huntington’s, I would not hesitate to be able to allow my child to have the best potential future I could provide. You know, as is your job and responsibility as a parent and steward of the future generation. Stronger, smarter, more resilient are all things future children will need because the past generations fucked the planet

  7. @ghosted1996

    October 29, 2026 at 12:16 pm

    I have schizoaffective bipolar and I’m conflicted about the possibility it could have been “erased” I would not be the same person nor have had the same experiences that shaped my passions and perspective. My life would be so different without these conditions that I can’t even imagine it. I also have several comorbid physical conditions that can accompany schizophrenia. With the science of embodied cognition I’m skeptical this wouldn’t entirely change the development of my personality as well, the way I think and move through the world, which does have benefits. There is evidence that bipolar and schizophrenia evolved to drive curiosity and knowledge accumulation, and much research has been done on associations with bipolar and creativity

  8. @jackmen4

    October 29, 2026 at 12:16 pm

    I’m all for eliminating really bad genetic disorders. But then for every good thing we make ten evil things follow. Has anyone seen the movie GATTACA. We already have selective health insurance denial, why bring in Genetics into it.

  9. @ekulerudamuru

    October 29, 2026 at 12:20 pm

    COORDINATORS, thats what gonna happen

  10. @PlayToe-u7i

    October 29, 2026 at 12:26 pm

    if parents could choose their children’s characteristics, we would see a very large number of tall, strong, blue eyed, blond, intelligent – BOYS.

  11. @jejejejejesss

    October 29, 2026 at 12:27 pm

    The science is amazing. Hopefully this doesn’t turn society into a GATTACA reality

  12. @Bread-b3m

    October 29, 2026 at 12:30 pm

    I usually pick Uniqlo jeans for my kids

  13. @Demonslayingqueen

    October 29, 2026 at 1:17 pm

    I won’t get biological children if there is a chance they can get sick genes or dangerousely broken genes resulting into a chronic lifetime decease. I would do a DNA test for my children IF I ever want to have children in the first place. If they posses one of the terrible deceases I would get those genes replaced in a heartbeat. If humanity would be on the brink of extinction, but your children wouldn’t have a future or a decent life then humanity can vanish. Not worth it so happy that science can do this for future generations!

    • @BonnieShadow33

      October 29, 2026 at 7:28 pm

      This isn’t about replacing their genes. It’s about rejecting the embryos you don’t want and implanting the embryo you do want. The others are destroyed (killed). This is eugenics.

  14. @karineassinka

    October 29, 2026 at 2:30 pm

    We already consider ourselves gods; soon we will create gods and kill those who are not up to our level of perfection. Difficult times are coming.😢😢

  15. @غونايآغا

    October 29, 2026 at 2:59 pm

    😢As an RP patient, I don’t know if I’ll have kids, and if I do, I don’t know if it’s better for them to be healthy since living healthy is wonderful, but living with illness is also wonderful, so I don’t know which one I prefer.

  16. @anneclareculpepper1344

    October 29, 2026 at 6:25 pm

    This is eugenics.

  17. @p4blo992

    October 29, 2026 at 7:17 pm

    Way too optimistic and undifferentiated opinion on a topic/technology which is highly complex and very potent to society at the same time. Sorry but the reflection side comes in way too short here. Quite unscientific and unethical if you ask me. We can talk about this topic, theres pros and cons, but not in this way please..

  18. @BonnieShadow33

    October 29, 2026 at 7:23 pm

    7:22 “Soon this is going to be the default way we all have babies.” You’re delusional if you really think that. Haven’t you ever seen poor people?!? How much money is your company making off your customers?!? You REALLY think the average person can afford this?? Don’t you know people in the USA are having to choose between healthcare and basic necessities?!? You completely lost me right here!

    And that’s aside from all the ethical questions!!

  19. @FiveRomeoCharlie

    October 29, 2026 at 7:27 pm

    Gattaca, here we come.

  20. @ArteDeSoltar

    October 29, 2026 at 7:57 pm

    Este video (0:00 – 13:02), presentado por Noor Siddiqui, explora el cambio de paradigma en la tecnología reproductiva, específicamente en la capacidad de leer y analizar el genoma completo de los embriones durante el proceso de fecundación in vitro (FIV).

    Puntos clave:

    • El fin de la “lotería genética”: Siddiqui argumenta que históricamente el ADN de un niño dependía del azar al momento de la concepción. Su empresa, Orchid, desarrolla herramientas de detección que permiten a los padres obtener mucha más información genética de la que ofrecía el cribado estándar (0:00 – 0:35, 0:52 – 2:05).
    • Salud y prevención: La ponente explica cómo este análisis ayuda a las familias a comprender y reducir riesgos de salud a largo plazo, identificando predisposiciones a enfermedades complejas (como diabetes, enfermedades cardíacas o ciertos tipos de cáncer) antes del nacimiento (2:10 – 2:40, 5:25 – 6:00).
    • Consideraciones éticas: Se plantea la pregunta central sobre cuánto deberíamos saber realmente sobre el ADN de nuestros hijos antes de que nazcan. Se mencionan casos de familias que han enfrentado tragedias debido a condiciones genéticas prevenibles (7:42 – 8:15).
    • Visión de futuro: La charla concluye con una sesión de preguntas y respuestas junto a Sal Khan (11:58 – 13:02), donde se discute la responsabilidad ética y el futuro del acceso a este tipo de tecnología médica avanzada.

  21. @ArteDeSoltar

    October 29, 2026 at 7:58 pm

    This video (0:00 – 13:02), presented by Noor Siddiqui, explores a paradigm shift in reproductive technology, specifically the ability to read and analyze the entire genome of embryos during the in vitro fertilization (IVF) process.

    Key takeaways:

    • The end of the “genetic lottery”: Siddiqui argues that, historically, a baby’s DNA was left to chance at conception. Her company, Orchid, develops screening tools that allow parents to access significantly more genetic information than standard testing offered (0:00 – 0:35, 0:52 – 2:05).
    • Health and prevention: She explains how this analysis helps families understand and reduce long-term health risks by identifying predispositions to complex conditions—such as diabetes, heart disease, or certain cancers—before birth (2:10 – 2:40, 5:25 – 6:00).
    • Ethical considerations: The talk raises a central question: How much should we know about our children’s DNA before they are born? It includes emotional stories of families who faced tragedies due to preventable genetic conditions (7:42 – 8:15).
    • Future vision: The session concludes with a Q&A alongside Sal Khan (11:58 – 13:02), discussing the ethical responsibilities and the future accessibility of this advanced medical technology.

  22. @ArteDeSoltar

    October 29, 2026 at 8:00 pm

    The technology presented by Noor Siddiqui (0:05:25-0:06:00) forces us to confront a difficult question: Where does medical prevention end and genetic selection begin? While the ability to reduce health risks is undeniably transformative, it opens a Pandora’s box of ethical dilemmas regarding how we perceive life and human variation.

    If you had the power to screen your future child’s genome to prevent disease, would you do it, or is there value in the ‘genetic lottery’ that we are risking by making these choices?

    – Si tuvieras el poder de analizar el genoma de tu futuro hijo para prevenir enfermedades, ¿lo harías, o crees que hay un valor intrínseco en la ‘lotería genética’ que estamos arriesgando al tomar estas decisiones?

  23. @xwingpilot1138

    October 29, 2026 at 9:03 pm

    This is eugenics, screw this

  24. @maepie

    October 29, 2026 at 9:26 pm

    eugenics 🤢

  25. @nao_kaka

    October 29, 2026 at 9:29 pm

    When listening to biotech founders pitch embryo screening as the default way everyone will have babies, it usually sounds like a dream, when in reality, that “30 to 50% risk reduction” across 5 sibling embryos for complex polygenic diseases is just relative risk—meaning a baseline 1% risk drops to 0.6%—while completely glossing over the weeks of hormone injections and egg retrieval surgery women have to endure for IVF. Though the funniest part was at [12:10] when Sal Khan asked where she draws the ethical line after she just teased superhuman endurance and unbreakable bones, and she basically shrugged and said “It’s really up to you guys”—probably the most classic Silicon Valley founder mic-drop disclaimer ever 😂

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