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How Do You Turn Setbacks Into Motivation? A Doctor + A Trauma Specialist Answer | TED Intersections

How do you hold on to hope while still being realistic about the work that needs to be done? Immunology researcher David Fajgenbaum and public health expert Celina de Sola discuss how they scaled personal missions into organizations making long-term impact on communities near and far. They explore how to stay motivated, discover your leadership…

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6 months ago

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How do you hold on to hope while still being realistic about the work that needs to be done? Immunology researcher David Fajgenbaum and public health expert Celina de Sola discuss how they scaled personal missions into organizations making long-term impact on communities near and far. They explore how to stay motivated, discover your leadership style and uncover overlooked solutions hiding in plain sight. (This conversation is part of “TED Intersections,” a series featuring thought-provoking conversations between experts navigating the ideas shaping our world.)

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11 Comments

11 Comments

  1. @LoriMcalroy

    September 23, 2025 at 11:01 am

    Hey Ted 👋

    Reply

  2. @LoriMcalroy

    September 23, 2025 at 11:04 am

    This couldn’t be more needed trauma n stress anxiety’s my middle name can’t believe im still here

    Reply

  3. @LoriMcalroy

    September 23, 2025 at 11:07 am

    I was thinking this yesterday when it came to ibs and gastrics problems

    Reply

  4. @Leto2ndAtreides

    September 23, 2025 at 12:09 pm

    What drug did you use for your Castleman disease?

    Reply

  5. @TheBestLifeMindsetWithShelly

    September 23, 2025 at 1:24 pm

    Inspiring conversation! I love the focus on turning hope into concrete action, such a powerful reminder that small, consistent steps create real change. 💖

    Reply

  6. @claires9100

    September 23, 2025 at 1:27 pm

    Holding despair and hope together is a very powerful concept. Hope in action is so important. This really resonates with me .

    Reply

  7. @MaiAnnChan

    September 23, 2025 at 2:58 pm

    Truly inspiring story,just what my nephew is doing in Toronto, Canada, smart man❤❤❤❤❤

    Reply

  8. @MaiAnnChan

    September 23, 2025 at 2:59 pm

    Great for those who are able to give their own TED talk❤❤❤❤😊🎉🎉❤❤

    Reply

  9. @innerrise.official

    September 23, 2025 at 7:58 pm

    It’s truly inspiring to hear how two incredible individuals are turning hope into tangible action, tackling massive challenges in healthcare and social systems.

    Reply

  10. @todaycountsshow

    September 24, 2025 at 4:39 am

    Holding hope and despair together fuels resilience, purpose, and meaningful impact. 🌱

    Reply

  11. @KkKk-t2c7d

    September 24, 2025 at 6:30 am

    My friend, I find that formal British English, like what we hear on the BBC, is clear and beautiful. But I also understand that it’s important to learn both formal and casual English at the same time.

    The challenge is that British casual English feels very difficult for me, and there are so many different regional accents.

    So my question is: would it be acceptable to focus on formal British English, while also learning American casual English? I feel that American casual English is much easier to follow than British casual English.!

    Reply

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People & Blogs

The Controversial Climate Tool Funding Real Change | Sandeep Roy Choudhury | TED

If a company plants trees to offset its pollution, is that climate progress — or is it greenwashing? Critics of carbon markets say it’s the latter. But Sandeep Roy Choudhury, who’s spent two decades financing climate projects from rural cookstoves to coastal forests, says the real failure is discouraging companies from even trying. Hear his…

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March 31, 2026

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If a company plants trees to offset its pollution, is that climate progress — or is it greenwashing? Critics of carbon markets say it’s the latter. But Sandeep Roy Choudhury, who’s spent two decades financing climate projects from rural cookstoves to coastal forests, says the real failure is discouraging companies from even trying. Hear his case for why we shouldn’t let perfection block meaningful action on climate change. (Recorded at TED Countdown Summit 2025 on June 17, 2025)

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How to Be a Great Listener | Maegan Stephens, Nicole Lowenbraun | TED

Have you ever left a meeting thinking: everyone talked, but nothing was achieved? Chances are that people were listening to each other, just not in the same way. Listening experts Maegan Stephens and Nicole Lowenbraun unpack the four different ways to listen, sharing a practical framework that could change how you respond, build trust and…

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2 days ago

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March 30, 2026

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Have you ever left a meeting thinking: everyone talked, but nothing was achieved? Chances are that people were listening to each other, just not in the same way. Listening experts Maegan Stephens and Nicole Lowenbraun unpack the four different ways to listen, sharing a practical framework that could change how you respond, build trust and get results — starting with just one simple question. (Recorded at TED@BCGon October 23, 2025)

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The TED Talks channel features talks, performances and original series from the world’s leading thinkers and doers. Subscribe to our channel for videos on Technology, Entertainment and Design — plus science, business, global issues, the arts and more. Visit to get our entire library of TED Talks, transcripts, translations, personalized talk recommendations and more.

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TED’s videos may be used for non-commercial purposes under a Creative Commons License, Attribution–Non Commercial–No Derivatives (or the CC BY – NC – ND 4.0 International) and in accordance with our TED Talks Usage Policy: . For more information on using TED for commercial purposes (e.g. employee learning, in a film or online course), please submit a Media Request at

#TED #TEDTalks #Communication

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Have you heard of aphantasia? Here’s what it is — and how to know if you have it #TEDTalks

Picture this: a rocket ship crash-lands on a planet, and an alien approaches the spacecraft. What do you see in your mind when you visualize this scene? For Alex Rosenthal (and many others), the answer is: absolutely nothing. Exploring the fascinating science of aphantasia, or the inability to generate mental images, he shows why our…

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2 days ago

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March 30, 2026

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Picture this: a rocket ship crash-lands on a planet, and an alien approaches the spacecraft. What do you see in your mind when you visualize this scene? For Alex Rosenthal (and many others), the answer is: absolutely nothing. Exploring the fascinating science of aphantasia, or the inability to generate mental images, he shows why our minds are much more different than we think.

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