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Why Scientists Are Stress Testing Tardigrades | WIRED

Tardigrades are microscopic animals so adaptable they can survive in some of the most extreme environments in the universe. Because of their durability, scientists are experimenting with them, trying to figure out just HOW much they can endure and what we can learn from it. Still haven’t subscribed to WIRED on YouTube? ►► Listen to…

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Tardigrades are microscopic animals so adaptable they can survive in some of the most extreme environments in the universe. Because of their durability, scientists are experimenting with them, trying to figure out just HOW much they can endure and what we can learn from it.

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Why Scientists Are Stress Testing Tardigrades | WIRED

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188 Comments

188 Comments

  1. WestOfEarth

    November 3, 2021 at 8:25 pm

    Should begin a breeding program to increase their size until we can have pet Tardigrades running around.

  2. D Beekman

    November 3, 2021 at 8:27 pm

    Tardigrades Riot, thousands of people killed, film at 11

  3. Stone Sommers

    November 3, 2021 at 8:36 pm

    That is cool, especially, the blood research. But when you said using it to preserve vaccines, red flags shot up for me. If exposed to viruses it seems like it might be able to adapt it in more sinister ways. Like one of those movies were science was trying to make the world a better place, but then killed it. I guess the new RNA vaccines wouldn’t be able to do anything since it is literally half of the blueprint, but wouldn’t want this research tried on the alive/half alive vaccines.

  4. Eirik Olsen

    November 3, 2021 at 8:49 pm

    It’s fascinating, but I just feel bad for the little guys…Poor tardigrades…

  5. RootedHat

    November 3, 2021 at 8:50 pm

    How do tardigrades react to drugs? Or gases? Or different fluids?

  6. BroAnarchy

    November 3, 2021 at 9:02 pm

    Mmmm….. _powdered _*_Blood_*

  7. L0united

    November 3, 2021 at 9:05 pm

    get ready to be tardigraded.

  8. Fabio C

    November 3, 2021 at 9:11 pm

    BarbascuraX made a cooler video on Tardigrades.

  9. Jake Dawg

    November 3, 2021 at 9:22 pm

    The future of travel they dry you up and ship you in a box when you reach your destination you are re hydrated

  10. surferguy837

    November 3, 2021 at 10:00 pm

    Ww.. wwww. Wwww. Wwwwaaaterbears

  11. Mandeep

    November 3, 2021 at 10:01 pm

    Awesome

  12. Supreme

    November 3, 2021 at 10:03 pm

    2:41 nice brave wilderness hat

  13. Tenrek

    November 3, 2021 at 10:03 pm

    WAKE UP MOM NEW TARDIGRADE VIDEO

  14. C G

    November 3, 2021 at 10:05 pm

    My BABIES!!! ????????????????

  15. BeryJensen

    November 3, 2021 at 10:08 pm

    Please don’t hurt them anymore!!!!!!!

  16. Melbo

    November 3, 2021 at 10:22 pm

    what if we put them at the center of an a bomb?

  17. Robert Erbes

    November 3, 2021 at 10:54 pm

    Tardigrades finance. Invest in the crypto now before it goes up. Blow it up

  18. D H

    November 3, 2021 at 11:19 pm

    A small price to pay for salvation.

  19. OneEarthMERGED

    November 3, 2021 at 11:34 pm

    Don’t be mean to water Bears ): tf

  20. glossaria2

    November 3, 2021 at 11:45 pm

    Yay, tardigrades! ????

  21. inkboopus

    November 3, 2021 at 11:56 pm

    tardigrades are my favorite!! i nearly audibly gasped when i heard thomas boothby i’ve read so many of his papers LMAO

  22. Grace Harper

    November 4, 2021 at 12:39 am

    These thinks are in the Quantum realm!! Lol I seen these in Ant-man and the Wasp!! ????✌????

  23. Ranjit Pelia

    November 4, 2021 at 12:58 am

    Has anyone thought about conducting single-cell RNAseq or Spatial Transcriptomics on these Water Bears?

  24. Jiamie Kori

    November 4, 2021 at 1:02 am

    This is where our tax dollars should go. R&D and science is the future!

  25. Pepop

    November 4, 2021 at 1:12 am

    They actually die if you put them in 100 degree water for a day, in addition to anther things they aren’t as strong as people hype them to be

  26. Laila Wemusa

    November 4, 2021 at 8:02 pm

    hellooo doctor hunter ????

  27. Pearl Of The Ocean

    November 4, 2021 at 8:09 pm

    Famous scientist T. Fushiguro knows them very well

  28. Ben Khaleq

    November 4, 2021 at 8:34 pm

    Can’t wait for the tardigrade rights movement

  29. WuffyPuffCouchy

    November 4, 2021 at 9:02 pm

    what if you put tardigrades in lava?

  30. i just sneezed like a beast send help

    November 4, 2021 at 9:08 pm

    bro leave them alone

  31. TheManStrato

    November 4, 2021 at 9:44 pm

    Next up on the test. Tardigrades vs a Hammer

  32. spy fox

    November 4, 2021 at 9:47 pm

    Pretty sure south Park already covered this

  33. winkloaf

    November 4, 2021 at 9:57 pm

    “Scientists are looking at how we can stress out tardigrades”
    School.

  34. Pou1gie1

    November 4, 2021 at 10:44 pm

    Dr. Hunter Hines is handsome

  35. MrDuck

    November 4, 2021 at 10:46 pm

    When he said COVID *clicks off video* just no, no more bias ness

  36. Spider-Man

    November 4, 2021 at 10:48 pm

    I hate microscopic life. I wish it did not exist.

  37. Isaiah B

    November 4, 2021 at 10:54 pm

    i wonder if we are tardigrades to something else bigger

  38. Jacobulous

    November 4, 2021 at 11:37 pm

    but what if the tardigrades don’t want to go to space

  39. Minato monoshi

    November 4, 2021 at 11:45 pm

    I would like to volunteer to have my dna rewritten full of tardigrade or octopus magic
    I promise to use my newfound power for good(mostly)

  40. Taime Melody

    November 4, 2021 at 11:51 pm

    Powdered blood isn’t really all that far fetched really. I mean we do have dehydrated sea monkeys, that’s not too far off.
    I wonder what it might do for stem cell research, or cases like adisons, parkinson’s or Alzheimer.

  41. Paul Crawford

    November 5, 2021 at 12:01 am

    They are cool little bears cause they are helping humanity and look cute and don’t complain… well at least we don’t think they do… and thats good enough for you if its good enough for me

  42. Christopher Nickels

    November 5, 2021 at 12:16 am

    Why? To keep that sweet grant money coming in!

  43. Trey

    November 5, 2021 at 12:16 am

    Owning the rockets for this research is the only cool thing Elon Musk has ever been a part of in his life.

  44. Garrett Scaccia

    November 5, 2021 at 12:19 am

    You laugh, but these methods will prove invaluable when the tardigrade uprising begins.

  45. Christopher Bentley

    November 5, 2021 at 12:53 am

    These are fake. Supposedly you can buy them like you would sea-monkeys. When you don’t find one in the kit they will just says “Oh, it died” or some other such non-sense. People are making up fake animals and using cgi to make “videos” of them. That is the truth, deal with it.

  46. Carlos Rodriguez

    November 5, 2021 at 12:56 am

    The blood thing got me in it. ????

  47. DH Schumann

    November 5, 2021 at 1:00 am

    If evolution itself were represented as an organism, Tardigrades are there.

  48. That person Ingénue

    November 5, 2021 at 1:06 am

    Straight up torturing my little buddies

  49. Cheese

    November 5, 2021 at 1:20 am

    Im finna inject tardigade cells in my blood to become god.

  50. Stefan Miletic

    November 5, 2021 at 1:24 am

    south park

  51. Sleepygarnet DSO

    November 5, 2021 at 7:55 am

    tardigrades : quit playin bruh. just send us to mars right now

  52. Willard Comeaux

    November 5, 2021 at 11:07 am

    Thought there were called water bears…seen them on animal planet most extreme top 10 a while back.

  53. Poet Satyr

    November 5, 2021 at 11:50 am

    S E A B E A R

  54. Alexa productions

    November 5, 2021 at 12:30 pm

    They look like they have the texture of shrimp

    Okay bye

  55. All Over The Place

    November 5, 2021 at 2:11 pm

    This was really inspiring!
    It’s a shame that more people aren’t
    promulgating good news like this.

  56. Ian Raguse

    November 5, 2021 at 3:00 pm

    Guess we are Gods after all.

  57. BlueAshes

    November 5, 2021 at 3:04 pm

    so…we also started as microscopic living thinghs..right?!…. what if this guys are the begining of a super and the next species to dominate the world?

  58. userbosco

    November 5, 2021 at 3:05 pm

    Do they bleed molecular acid?

  59. Peter Morrison

    November 5, 2021 at 3:22 pm

    7:17
    bioweapons around the corner…. or already here?

  60. Hostey

    November 5, 2021 at 3:57 pm

    Tardigrades are just built different

  61. Julian H

    November 5, 2021 at 4:20 pm

    I am 100% expecting a tardigrade uprising in the next 50 years because of our little experiments here. One of these days it’ll evolve into dog-size and we’ll be screwed

  62. WeeWeeJumbo

    November 5, 2021 at 4:25 pm

    tardy graves

  63. Linda Scoon

    November 5, 2021 at 4:44 pm

    Poor little things. Leave them alone!

  64. Alexander Harlent

    November 5, 2021 at 5:31 pm

    This reminds me of godzilla for some reason

  65. Eden S. Lucf

    November 5, 2021 at 6:20 pm

    If what you’re saying about experiments is true, I wonder how the tardigrades’ DNA would mix with human DNA and how would you test these humans if they had this vaccine? This video has been thought-provoking.

  66. 561 Surya Gowtham

    November 5, 2021 at 7:18 pm

    They’re immortal

  67. sboulderickmam

    November 5, 2021 at 8:51 pm

    Sounds like a lot of torture and killing of those cute harmless hardy water bears.

  68. Eeezaack

    November 5, 2021 at 11:10 pm

    South park

  69. Nathan Brown

    November 5, 2021 at 11:11 pm

    Need a way to navigate the mycellium

  70. jimbobbyrnes

    November 5, 2021 at 11:21 pm

    imagine being injected with freeze dried blood just because its cheaper than the real blood they use for rich people. that is the dystopian future we seem to be heading too.

  71. Tracy Riverdeep

    November 5, 2021 at 11:39 pm

    Cool !!! Great video ❤️

  72. Kryptonite

    November 5, 2021 at 11:57 pm

    yeah… that guy’s real name is actually dr. michael morbius

  73. backtoids

    November 6, 2021 at 12:26 am

    nooooooooo :/ dont hurt them :((

  74. 04 Slobra

    November 6, 2021 at 1:23 am

    “Very good microbial predators”

    *belly full of algae*

  75. Sam S

    November 6, 2021 at 4:20 pm

    “Tardigrades are microscopic animals so adaptable they can survive in some of the most extreme environments in the universe.”

    *Find a way to pay for rent, healthcare, and food on a minimum wage salary, I’ll give the Tardigrade a week.*

  76. JStuff

    November 6, 2021 at 4:23 pm

    What in the south park

  77. MenTaLisKing

    November 6, 2021 at 5:22 pm

    Animal abuse, Dr. Fauci would be proud

    • MenTaLisKing

      November 6, 2021 at 5:23 pm

      omg they’re even trafficking these abused animals to one another

  78. Sharky & George

    November 6, 2021 at 5:44 pm

    They are cute? I can only imagine on what this guy jerks too.

  79. Suraj 18M

    November 6, 2021 at 5:59 pm

    Who else remember the south park episode of evolving tardigrades

  80. Andy

    November 6, 2021 at 6:43 pm

    Haha… Boothby

  81. Esaye Fishatsyen

    November 6, 2021 at 7:03 pm

    They survive because their small.

    • Mr.Fishstick _YT

      November 6, 2021 at 11:18 pm

      No.

  82. Erica McQueen

    November 6, 2021 at 7:07 pm

    So, Tardigrades are pretty much indestructible. They can survive the vacuum of space, he pressure of the sea, the cold and heat, yet we keep torturing them.
    I’m just saying, we probably shouldn’t make an enemy of them. This kinda sounds like the origin story of a villain. I hope the scientists stop this before the Tardigrades decide to get their revenge.

  83. BlackHeart Gaming

    November 6, 2021 at 7:44 pm

    Kipo where you at

  84. Kobe Dogg

    November 6, 2021 at 8:33 pm

    Imagine if there was an outside organism or beings stress testing humans

    • Goldenoodles

      November 6, 2021 at 8:40 pm

      Sooooo? Society?

  85. Orion

    November 6, 2021 at 9:58 pm

    4:56 Ive seen this movie before and it doesn’t end well

  86. Water Monstrosity

    November 6, 2021 at 10:11 pm

    They’re kinda cute-

  87. Primo Fiamma

    November 6, 2021 at 10:32 pm

    So Shia Labeouf is a scientist now ????

  88. Travis Cartee

    November 6, 2021 at 11:00 pm

    Tard

  89. Austin W.

    November 6, 2021 at 11:06 pm

    i read this as stress eating and i have to say tardigrades do not sound very nutricious

  90. Imagine Dweebus

    November 6, 2021 at 11:14 pm

    Wasn’t this a South Park episode

  91. X94

    November 6, 2021 at 11:26 pm

    Do they feel pain?

  92. ROM HEADLINER

    November 6, 2021 at 11:35 pm

    POWDERED BLOOD!!!!

  93. airbound

    November 6, 2021 at 11:53 pm

    How many have to die before making a philosophers stone

  94. Redd Asset

    November 6, 2021 at 11:57 pm

    Maybe in 20 years we can make like a type of Organic types of Armor

  95. Angel Gonzalez

    November 7, 2021 at 12:09 am

    Because they found out the tardigrades are masochists, but they forgot their safe word

  96. matthew mann

    November 7, 2021 at 12:13 am

    Yeah so radioactive, microscopic, hidden, and stealthed so up there yeah

  97. theverytiredbirb

    November 7, 2021 at 12:43 am

    They’re so gonna get revenge and kill us billions+ of years out for this

  98. Bubz

    November 7, 2021 at 1:15 am

    Now who tf is stress testing me??

  99. Nestly Manahan

    November 7, 2021 at 1:19 am

    I have never heard of these Tardigrades but I’m glad YouTube recommended this vid to me.

  100. Chad Buckle

    November 7, 2021 at 6:20 am

    Its all fun and games until the Qu treats humans like how we treat tardigrades.

  101. Ralphe Ralphe

    November 7, 2021 at 6:46 am

    Powdered blood? How about powdered ice cream?!

  102. Jaime Martinez

    November 7, 2021 at 7:13 am

    Cause they got everything else wrong.

  103. leon koek

    November 7, 2021 at 7:18 am

    vampire? lolz

  104. Ryoga

    November 7, 2021 at 7:26 am

    maybe have them give an oral presentation.

  105. Fer F

    November 7, 2021 at 7:27 am

    面白い。。

  106. Jesse Jamez

    November 7, 2021 at 8:14 am

    Such cute!
    Let’s torture them!
    *Dont worries it’s for SCIENCE* ????????????

  107. Mohammed Zaid Sikander

    November 7, 2021 at 8:53 am

    The scientists are about to make a…..discovery

  108. At D

    November 7, 2021 at 12:07 pm

    They’re cute, so let’s torture them to see what they can endure. ????

    • retard

      November 7, 2021 at 1:29 pm

      You eat and kill thousands of them everyday without knowing too though lol

  109. pork steam bun

    November 7, 2021 at 1:27 pm

    theyre so cuteee

  110. Malaysian Tropikfusion

    November 7, 2021 at 2:06 pm

    Those are some cute doctors. Just saying.

  111. Yoda

    November 7, 2021 at 4:09 pm

    As a microbiologist it’s actually it is

  112. Ambuck G

    November 7, 2021 at 4:10 pm

    I’d be down to try some tardigrade protien

  113. william

    November 7, 2021 at 4:17 pm

    After watching life I dont like those

  114. Avengers07

    November 7, 2021 at 4:20 pm

    *Tardigrades are really weird but they help us if we know their secret to live in extreme conditions….*

  115. g g

    November 7, 2021 at 4:29 pm

    UPDATE! Tarnigrades can now be recognized as people or “interested persons” with legal rights in the U.S. following a federal court order.

  116. Sture Jonsson

    November 7, 2021 at 5:20 pm

    Hi! I dont like so match stress????

  117. Syed

    November 7, 2021 at 6:47 pm

    Stranger Things!

  118. ً

    November 7, 2021 at 8:47 pm

    Dr. Boothby hahahaha that sounds like a cartoon doctor

  119. Joe Gar

    November 7, 2021 at 8:58 pm

    I’m calling PETA and tell how you’re stressing water bears.

  120. Aaliq Moin

    November 7, 2021 at 9:32 pm

    The applications of this project kinda let me down.. I was thinking more like they could help humans swim in lava or liquid nitrogen lol

  121. Daniel G.

    November 7, 2021 at 9:39 pm

    These are like microscopic real-life metroids.

  122. Itaka4k

    November 7, 2021 at 11:20 pm

    “Water bear don’t care” -????

  123. jack black

    November 7, 2021 at 11:40 pm

    T H I C C

  124. Frank S.

    November 8, 2021 at 2:07 am

    Researchers found that tardigrades can consistently beat Joe Biden at checkers.

  125. Angelo

    November 8, 2021 at 2:13 am

    ????????⚫????????⚛

  126. PurpleOtakuBB

    November 8, 2021 at 2:59 am

    The powered blood seem interesting…

  127. Dariush Silal

    November 8, 2021 at 3:05 am

    FACINATING

  128. JeSuisPasVacciné

    November 8, 2021 at 4:06 am

    Dr nozman on es la

  129. Peter Ward

    November 8, 2021 at 6:19 am

    Time And Relative Dimensions In Gravity?

  130. Ana Medina

    November 8, 2021 at 8:17 am

    He sounds like a deranged scientist who ends up as a criminal in one of those action movies lolol

  131. Khalid Syaufi

    November 8, 2021 at 8:27 am

    Where do they got money to do these experiments?

  132. V

    November 8, 2021 at 9:02 am

    this seems like after experimenting it on humans, scientists are gonna give birth to a Jason Voorhees

  133. rad sad dad

    November 8, 2021 at 9:39 am

    appa

  134. rad sad dad

    November 8, 2021 at 9:42 am

    hey that’s microscopic appa

  135. omnpHugs

    November 8, 2021 at 11:16 am

    South Park

  136. uj im

    November 8, 2021 at 11:49 am

    Where can i find them?
    I want to taste them

  137. Mohamed Ahmed

    November 8, 2021 at 1:53 pm

    I COULD HAVE SEEN THIS VIDEO I HAD TO DO A PRESENTATION EXPLAINING IF THEY ARE LIVING OR NON-LIVING
    (I got a 20/25 btw)

  138. Gio Fool

    November 8, 2021 at 3:32 pm

    Anyone here knows Captain Tardigrade?

  139. Waqar Haider

    November 8, 2021 at 5:56 pm

    some tough mfs

  140. terminator3000

    November 8, 2021 at 8:22 pm

    In germany we call them “bärtierchen” (bear animal, while the suffix “chen” generally mean that something is small) or “wasserbären” (waterbears) because the way they move looks a bit like a bear.

    Edit: i just heard that guy call them water bears at 5:10 . So, we are not the only ones calling them bears?

  141. Amur Ika

    November 8, 2021 at 11:20 pm

    Abusers… one day it will pay back exactly the same way… It will remember…

  142. Saitama Pistola

    November 9, 2021 at 12:49 am

    Na mora Youtube eu não tenho o mínimo interesse nessa porra para de me mandar

  143. Ray Vasquez

    November 9, 2021 at 2:18 am

    The nfl would like to know your location

  144. Mark Furst

    November 9, 2021 at 2:28 am

    The aliens are here

  145. withblue

    November 9, 2021 at 3:03 am

    theyre like real life slime theyre isekai-ed

  146. Ihtesham Emon

    November 9, 2021 at 5:38 am

    This is just amazing!

  147. Melissa Pyle

    November 9, 2021 at 7:40 am

    As resilient as these little guys r, one day they will have their revenge on humans for all their mistreatment..

  148. Midhun Arja

    November 9, 2021 at 8:54 am

    Marvel found the origin of its next superhero

  149. KRUSHNA CHAUGULE

    November 9, 2021 at 10:14 am

    Lol

  150. SAURAV KUMAR

    November 9, 2021 at 10:58 am

    It’s not an animal it’s a microbe

  151. Abhishek Bhowmik

    November 9, 2021 at 1:37 pm

    Me, a gamer and Kojima fan: Hey look, a cryptobiote

  152. じゃま

    November 9, 2021 at 2:19 pm

    poor tartigrades????

  153. Unfazed Render

    November 9, 2021 at 3:37 pm

    animal abuse

  154. Mobile Notherwise

    November 9, 2021 at 4:54 pm

    nuke it

  155. Delirious Mysterium

    November 9, 2021 at 5:03 pm

    So this is what joe rogan was talking about with GAIN OF FUNCTION

  156. Master Cheif

    November 9, 2021 at 8:35 pm

    Why is south park always ahead of the curve… They have thier finger on the pulse of EVERYTHING

  157. I agree with you

    November 9, 2021 at 8:35 pm

    Y’all gonna regret this. As if you haven’t seen enough sci fi movies already.

  158. Mr. DIPERSON GHISING

    November 10, 2021 at 4:02 am

    But can it survive a Heartbreak?

  159. VAIBHAV RAJ

    November 10, 2021 at 7:16 am

    I know them because of antman and the wasp quantam journey.
    Tardigrades have super abilities.

  160. VibrantVirtue

    November 10, 2021 at 9:21 am

    Boop

  161. Joel InThePalace

    November 10, 2021 at 10:31 am

    Next:
    How zombie apocalypse started.

  162. Shaurya Bansod

    November 10, 2021 at 11:32 am

    7:24….
    Aww it would be so cute to create a bacteria with properties of a virus!

    It was a joke! Dead af

  163. R.S.

    November 11, 2021 at 1:23 am

    2:26 is this the same place Ryan Trahan stayed?

  164. someone give me a name

    November 11, 2021 at 1:24 am

    Funny how some people here are feeling pity for predator bacteria XD

  165. Abhishek Kumar

    November 11, 2021 at 8:11 am

    These are some itch causing b@s***ds, I have experienced it

  166. Utkarsh Gaikwad

    November 11, 2021 at 8:28 am

    If tardigrades survive in space aren’t us sending them may someday in future lead to them evolving into aliens which may be infact created by humans?

  167. Axe M.

    November 11, 2021 at 12:49 pm

    Dale Stayne

  168. EndlessDrive

    November 11, 2021 at 7:52 pm

    After watching this, I now want a tardigrade plushie to clip on the side of my monitor lol

  169. Bit Rage

    November 11, 2021 at 11:46 pm

    THATS IT!!! Im starting a Tardigrade abuse campaign!!! #SaveTheLilBears

  170. Yozume

    November 12, 2021 at 2:55 am

    Why can’t we just take the immunity of tardigrades so we could be immune too?

  171. Michael Michael's

    November 12, 2021 at 3:41 am

    Covid will kill it! I’ll mandate it…..

  172. Nauman Sayyad

    November 12, 2021 at 6:20 am

    Humans:Woww tardigrades are so cute
    Also humans:shoot them out of a gun
    Meanwhile tardigrades:Why you bully me?

  173. Deadhead Wannabe

    November 13, 2021 at 6:38 am

    Sad they killed them….my new favorite animal

  174. Deadhead Wannabe

    November 13, 2021 at 6:39 am

    I love their feet

  175. Relaxing.sleep47

    November 13, 2021 at 10:51 am

    I am poor.

  176. MrWil Vlogs

    November 13, 2021 at 11:44 am

    Amazing micro work..i hope i can see in my own microscope. But need to upgrade mine first.

  177. dear Oo

    November 13, 2021 at 3:36 pm

    I am here thinking how they taste is it possible to eat them?

  178. freesouljah

    November 13, 2021 at 5:48 pm

    Scientists: Let’s make powdered blood
    Vampires: Let’s snort a few lines

  179. Animals_Matter2

    November 13, 2021 at 8:09 pm

    how do you expect to go to another planet when society cant even take care of earth… ???? doesnt make sense …

  180. LightBringer 307

    November 14, 2021 at 6:08 am

    1:34
    Does that A stand out to anybody else? It seems out of place to me somehow and I don’t know why.

  181. Xiom Greninja

    November 15, 2021 at 11:45 am

    Cute?

  182. Danny Archer

    November 16, 2021 at 3:14 am

    NASA: We’ve found life on Mars!!
    Everyone: Yaaaaaaaaaaaaaaaaaaaaaaaaay!!!
    NASA: They’re tardigrades.
    Everyone:

  183. Omaer 1

    November 18, 2021 at 6:13 pm

    Very Nice Bro! Get Good. MashAllah(SWT).

  184. Brandon Rondelli

    November 19, 2021 at 12:56 pm

    Imagine all your micro biome become water bear grade inhabitants

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Science & Technology

Learn What VCs Actually Want, From a Founder Who’s Raised $1B l Build Mode

Investors want founders who understand the financial reality of their business. Messy data, misunderstood metrics, or waiting until you’re nearly out of cash to start fundraising can cost founders leverage, valuation, and even a term sheet. In this episode of Build Mode, host Isabelle Johannesen sits down with Sasha Orloff, founder and CEO of Puzzle…

Published

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Investors want founders who understand the financial reality of their business. Messy data, misunderstood metrics, or waiting until you’re nearly out of cash to start fundraising can cost founders leverage, valuation, and even a term sheet.

In this episode of Build Mode, host Isabelle Johannesen sits down with Sasha Orloff, founder and CEO of Puzzle and Startup Battlefield alum, to talk about what he’s learned from building companies that have raised more than $1 billion collectively.

Sasha breaks down what investors look for during fundraising, which financial metrics founders should know by heart, and why VCs don’t expect your startup to be perfect—they expect you to understand its reality. He also shares how he nearly lost a term sheet because his data room wasn’t ready, how fundraising diligence changes as a startup grows, and why getting your financial house in order can help founders raise with more confidence and leverage.

They get into:
– What raising more than $1 billion across multiple companies taught Sasha about fundraising
– Why investors value founders who have a strong grasp of their company’s financial reality
– The financial metrics founders should know before pitching VCs
How investor expectations change from pre-seed and seed through Series A, B, and beyond
– Why revenue growth and the quality of that revenue are critical fundraising metrics
– How runway, margins, sales efficiency, and profitability factor into investor decisions
– Why waiting until you’re running out of cash can hurt your fundraising leverage
– How Sasha nearly lost a term sheet because his data room wasn’t ready
– Why financial organization and compliance can influence investor confidence and startup valuations
– What founders should have prepared for the due diligence process
– Why VCs don’t expect perfection—and why being honest about what isn’t working can make for a stronger pitch
– How Sasha’s own fundraising and finance frustrations ultimately led him to build Puzzle
– How AI could change the way startups manage accounting and understand their financial health

Chapters:
00:00 – Why VCs Want Founders Who Understand Reality
01:26 – Sasha Orloff’s Journey to Building Puzzle
05:05 – Why Puzzle Started With Startup Founders
08:38 – What Founders Should Know Before Fundraising
11:08 – What Investors Look for During Due Diligence
14:37 – Understanding the Financial Health of Your Startup
17:52 – The Financial Mistakes Founders Make
20:19 – When Startups Need Accountants and Finance Teams
24:04 – How Sasha Almost Lost a Term Sheet
26:10 – The Financial Metrics Founders Should Know Cold
28:20 – Lessons From Raising $1B+ Across Multiple Companies
31:45 – Why Financial Readiness Matters to Investors
33:49 – How AI Is Changing Startup Accounting
37:17 – Inside Puzzle’s Series A With General Catalyst
38:52 – Launching Puzzle at Startup Battlefield
40:38 – Sasha’s Advice for Early-Stage Founders

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Science & Technology

How Satellites and AI Can Protect the Planet | Robbie Schingler | TED

Space technologist Robbie Schingler cofounded a satellite company that images the whole planet every day, making visible changes on Earth. He shows how pairing that data with AI creates a “planetary intelligence” we can use to spot emerging threats we might not have seen otherwise. Now he asks: Can we close the gap between seeing…

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Space technologist Robbie Schingler cofounded a satellite company that images the whole planet every day, making visible changes on Earth. He shows how pairing that data with AI creates a “planetary intelligence” we can use to spot emerging threats we might not have seen otherwise. Now he asks: Can we close the gap between seeing a crisis coming and actually stopping it? (Followed by a note from TED guest curators Divya Siddarth and Audrey Tang) (Recorded at TED2026 on April 14, 2026)

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The TED Talks channel features the best talks and performances from the TED Conference, where the world’s leading thinkers and doers give the talk of their lives in 18 minutes (or less) — plus originals, podcasts and exclusive content. Look for videos on Technology, Entertainment and Design as well as science, business, global issues, the arts and more. Visit for our entire library, transcripts, translations and personalized recommendations.

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#TED #TEDTalks #Tech #ClimateChange

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CNET

That Voicemail Isn’t Real, It’s AI. The New Wave of AI-Impersonation Scams

Scammers are using AI to impersonate high-profile targets, such as celebrities and politicians. Here’s how you can stay safe. You can find the products mentioned in this article linked below Commerce Link *CNET may get a commission on these offers Link to CNET article: Read more about X on CNET.com: Timecode Chapters: 00:00 The Threat…

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Scammers are using AI to impersonate high-profile targets, such as celebrities and politicians. Here’s how you can stay safe.

You can find the products mentioned in this article linked below
Commerce Link
*CNET may get a commission on these offers

Link to CNET article: Read more about X on CNET.com:

Timecode Chapters:
00:00 The Threat of AI Impersonation
01:25 How Deepfakes Are Used in Politics
04:07 The Rise of Hyper-Personalized Fraud
05:42 Testing a Voice Clone on My Boss
07:11 Audio Blind Taste Test With My Sister
11:10 How to Stay Vigilant Against AI Clones

Video Credits:
Host: Katelyn Chedraoui
Scripted by:Katelyn Chedraoui
Producer: Numi Prasarn
Camera: Carly Marsh
Video Editor: Jon Gomez
Thumbnail Designer: Zooey Liao

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