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Can Ozempic End Addiction? | Dhruv Khullar | TED

What if GLP-1s like Ozempic could do more than just tip the scales? Physician Dhruv Khullar traces the winding path of the “moderation molecule” — from a discovery in Gila monster saliva to a potential diabetes medication and addiction treatment — and how they could quiet the relentless noise of craving. The most surprising effects…

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What if GLP-1s like Ozempic could do more than just tip the scales? Physician Dhruv Khullar traces the winding path of the “moderation molecule” — from a discovery in Gila monster saliva to a potential diabetes medication and addiction treatment — and how they could quiet the relentless noise of craving. The most surprising effects of GLP-1s may not be in the gut, but in the brain. (Recorded at TED2026 on April 15, 2026)

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34 Comments

34 Comments

  1. @pryingopenmythirdeye13

    July 9, 2026 at 11:05 am

    Woah, this is definitely going to be interesting.

  2. @Doc_Aizaz

    July 9, 2026 at 11:10 am

    After few years, scientists will comeup and will say… we were wrong.. happened many times in history, certain drugs were approved and were called as magical drugs on that time for certain diseases but somehow few years later…drastic side effects were noticed…

    • @aconb2120

      July 9, 2026 at 12:05 pm

      @Doc_Aizaz example?

    • @oxymoron500

      July 9, 2026 at 12:21 pm

      That happens sometimes, but not always

    • @The_winds_of_change

      July 9, 2026 at 2:13 pm

      Nonsense.
      This is the greatest medical breakthrough since the discovery of penicillin.

    • @Doc_Aizaz

      July 9, 2026 at 2:19 pm

      ​@The_winds_of_change wow great just go through the side effects.. I’d mention one of the, the retinopathies… the lethal one…
      After every new drug is launched, the side effects are hidden for few years..
      Pharmaceutical is now an industry, doesn’t care about humanity anymore

    • @The_winds_of_change

      July 9, 2026 at 2:24 pm

      ​@Doc_Aizazpharmaceuticals have always been an industry, the very nature of procuring, processing, manufacturing and delivering makes something an industry.
      Its independent government policing of healthcare that isnthe issue, and i consider myself very fortunate that, despite its flaws, i live in england where my healthcare costs a pittence.

  3. @daledevernon56

    July 9, 2026 at 11:11 am

    The problem with this drug in particular is that it is not a cure it is a band-aid and you would have to be on it for a long period of time and your family won’t recognise you anymore because they wouldn’t know if you are on ozempic or crack.

    • @oxymoron500

      July 9, 2026 at 12:20 pm

      @daledevernon56 “Your family won’t recognize you anymore”. Any source for that?

    • @Stebon6480

      July 9, 2026 at 12:36 pm

      I’m not sure you are doing anything more than speaking from ignorance.. You do know that getting clean takes a process of rewiring the neuropathways, and changing habits that keep addicts using.. A band aid has an important function. I mean this to say, it’s not a magic bullet but that doesn’t mean its not useful. In order to recover there needs to be abstinence for a significant amount of time. If this can do that, then addicts can stop long enough to gain clarity and achieve the next step. Complete abstinence is part of the process. Of course there are many working parts to ones sobriety. Addicts might consider anything when they have nothing.

    • @Stebon6480

      July 9, 2026 at 12:38 pm

      But I know you were trying to be funny bc both would make you lose weight… Haha…lame

  4. @burgundysopathiccreativiti2602

    July 9, 2026 at 11:14 am

    Ozempic is an addiction. Don’t believe me? Look at the craze for it.

    • @The_winds_of_change

      July 9, 2026 at 11:32 am

      @burgundysopathiccreativiti2602  that’s not what an addiction is.
      Yours sincerely, a recovering crack cocaine addict.

    • @jacquelineburns2731

      July 9, 2026 at 11:43 am

      @burgundysopathiccreativiti2602 or…people finally feel so much better, and feeling better than you have for years and years is the addiction.

    • @studyireland

      July 9, 2026 at 12:51 pm

      @burgundysopathiccreativiti2602 like using a hoola hoop

  5. @PeriOdotGladiOlus

    July 9, 2026 at 11:28 am

    I have a friend who says her GLP-1 totally killed her cravings for alcohol and sugar, and that ultimately that’s why she lost so much weight. Cool to see her lived experience backed up by the latest clinical data!

  6. @Rushingpastfailure

    July 9, 2026 at 11:30 am

    Watching this whilst drinking…

  7. @Rushingpastfailure

    July 9, 2026 at 11:34 am

    What a great guy

  8. @The_winds_of_change

    July 9, 2026 at 11:36 am

    People in the comments have clearly not had to suffer through what i and so many other addicts have to endear when we take the plunge to try and rid outselves of whatever vice we may be addicted to.
    The cripplijg anxiety and nausea in our stomachs, the fixation on the association of money and a fix, unable to mentally mature past whatever age our recreational use evolved into dependence… i could go on, i really could.
    If these pharmaceuticals can truly help give an addict such as i a slightly less rough ride when outgrowing our addiction then i for one would certainly take it, if it means i could sleep and not be wsking every hour with cravings.

    • @DabsOnDabs

      July 9, 2026 at 5:51 pm

      No amount of ozempic is going to keep someone away from heroin if that’s their active DoC.

  9. @jadeg1095

    July 9, 2026 at 11:41 am

    It quiets everything. Like a zombie

  10. @angelicabanuelos9200

    July 9, 2026 at 11:48 am

    Replacing one bad habit with another, how about quitting cold turkey?

    • @jondevere4918

      July 9, 2026 at 12:04 pm

      @angelicabanuelos9200 oh yeah, cos no addict has ever thought of this before.
      If only it was as easy as commenting on a YouTube video….

    • @toolthoughts

      July 9, 2026 at 4:35 pm

      tapering is much safer with almost any substance

  11. @Getitgetit1983

    July 9, 2026 at 12:15 pm

    Can confirm. I started 4 weeks ago and have had prior substance dependence issues. I have been telling people this message for the last month.

  12. @GreatVomitto

    July 9, 2026 at 12:15 pm

    Yes because it destroys you liver and, you either die or get proper help.

  13. @marcotesti6393

    July 9, 2026 at 12:23 pm

    It can certainly make you look like a drug addict.

  14. @welcome.421

    July 9, 2026 at 12:59 pm

    TED | Help me for better again🙏🏼

  15. @Maroof9011-m6y

    July 9, 2026 at 12:59 pm

    For years, manifesting felt like something just out of my reach. One day I decided to try Vera Hart’s archetype quiz, and it changed everything. My result matched exactly who I am, and only then did I understand how it really works. If you’re struggling with it too, give it a chance. It only takes a few minutes. ❤️

  16. @SteveC-Shaman

    July 9, 2026 at 1:06 pm

    retatrutide sure can… it makes beer taste like fermented grains in water… in the worst way

  17. @toolthoughts

    July 9, 2026 at 4:32 pm

    this week in how naive can you be

  18. @saeedseify2131

    July 9, 2026 at 6:12 pm

    Hi I’m Iranian and here is war I’m so depress please help me 😢😢😢😢

  19. @Man-yw

    July 9, 2026 at 7:52 pm

    And then you get addicted to ozempic

  20. @GarrettKrahn1

    July 9, 2026 at 8:06 pm

    TED has jumped the shark

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