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The Brilliance of Bacteria (and How They Combat Waste) | Patricia Aymà Maldonado | TED

Bacteria are the most incredible creatures on Earth, says biotechnologist and TED Fellow Patricia Aymà Maldonado. She presents a groundbreaking technology that “trains” bacteria to transform organic waste into biodegradable plastic that behaves like the real thing. Learn how this creative, sustainable approach could revolutionize the plastics industry. (Recorded at TED Fellows Films 2025 on…

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Bacteria are the most incredible creatures on Earth, says biotechnologist and TED Fellow Patricia Aymà Maldonado. She presents a groundbreaking technology that “trains” bacteria to transform organic waste into biodegradable plastic that behaves like the real thing. Learn how this creative, sustainable approach could revolutionize the plastics industry. (Recorded at TED Fellows Films 2025 on April 7, 2025)

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15 Comments

15 Comments

  1. @samikbloxy

    January 16, 2026 at 11:04 am

    First comments!

  2. @chisom_inspires

    January 16, 2026 at 11:06 am

    Literally watching all videos

  3. @alesmarting

    January 16, 2026 at 11:31 am

    less talk and more action

  4. @QuickClarity-TV

    January 16, 2026 at 12:03 pm

    very inspiring actually i love it

  5. @PlasticBank

    January 16, 2026 at 12:12 pm

    It’s amazing how the smallest life forms might help clean up the biggest mess humans made!

    • @DerhanaSitymunawaroah

      January 16, 2026 at 9:17 pm

      It’s nice to heard😊

  6. @AcselMitchell

    January 16, 2026 at 12:27 pm

    bacteria lovato!

  7. @ExistentialWolf

    January 16, 2026 at 5:21 pm

    Plastic is a term borrowed from material properties, with elastic being the contrast, for example. The complexity of reusing “plastics” is that there are many forms. I could write you a recipe to liquify any combination, but you need to sort that out 😀 Yes, there is a _method_ to do them all at once, but it’s further from your direction. The bugs are a fun one though … you never quite know if you’re cultivating correctly do you??

  8. @xXah

    January 16, 2026 at 6:08 pm

    laggy video 🙁

  9. @thepeopleslight

    January 16, 2026 at 10:40 pm

    Nature already had the solution. We just weren’t listening

  10. @changeorbeextinct

    January 16, 2026 at 10:53 pm

    Ok, love your bacteria folks

  11. @0055-g3i

    January 17, 2026 at 5:22 am

    Thanks the microorganism and thanks for your contribution

  12. @jurjenbos228

    January 18, 2026 at 11:43 am

    “Plastic is not the problem, it is how we produce it, use it and dispose of it.”

  13. @dhruboshahriar-sv7pr

    January 19, 2026 at 2:18 am

    Mind blowing 🤯

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Science & Technology

The VC Backing the American Dream with Manan Mehta, Unshackled Ventures

Immigrant founders have built some of the world’s most valuable companies, but many still face barriers that make it harder to get a startup off the ground. Visa restrictions, limited access to friends-and-family capital, shallow networks, and a venture industry built around pattern matching can keep promising founders from getting funded before they have a…

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Immigrant founders have built some of the world’s most valuable companies, but many still face barriers that make it harder to get a startup off the ground. Visa restrictions, limited access to friends-and-family capital, shallow networks, and a venture industry built around pattern matching can keep promising founders from getting funded before they have a chance to prove themselves.

In this episode of Build Mode () , host Isabelle Johannesen sits down with Manan Mehta, co-founder and managing partner of Unshackled Ventures, () to talk about why he believes immigrant founders represent one of venture capital’s biggest overlooked opportunities. Manan breaks down how Unshackled built an investment model designed to help founders navigate immigration barriers, why traditional VC pattern matching causes investors to miss potential outliers, and how his team evaluates founders at day zero—often before they have a product, customers, or traction. He also explains why the structural gaps that make some founders harder to fund may be exactly where investors should be looking for outsized returns.

They get into:

The four structural barriers immigrant founders face when starting companies in the U.S.

How Unshackled Ventures helps founders navigate visas while building their startups

Why VC’s reliance on pattern matching can cause investors to miss outlier founders

How Manan evaluates founders before they have a product, customers, or traction

The IQ, AQ, EQ, and SQ framework Unshackled uses to evaluate founder potential

Why resilience, lived experience, and a founder’s relationship to the problem can matter more than a polished pitch

Why structural gaps can create some of the biggest opportunities for investors

How founders without traditional networks can find alternative paths to early capital

Why founders should understand their personal “why” instead of trying to fit the traditional VC mold

Subscribe to Build Mode on Apple Podcasts () , Spotify () , or wherever you like to listen () . And watch the full videos on YouTube () . New episodes of Build Mode () drop every Thursday.

Chapters:

00:00 – Why VCs Miss Outlier Founders

01:45 – Why Manan Mehta Founded Unshackled Ventures

04:15 – The Problem With VC Pattern Matching

06:15 – The Friends-and-Family Gap for Immigrant Founders

08:18 – How Unshackled Helps Founders Navigate Visas

10:40 – Building a Startup in Today’s Immigration Environment

12:19 – Solving One of Unshackled’s Hardest Immigration Cases

14:39 – What the U.S. Stands to Lose16:59 – Raising Unshackled’s First Venture Funds

19:40 – Can You Start a Company on an H-1B Visa?

22:13 – How to Evaluate a Founder at Day Zero

28:30 – Measuring IQ, AQ, EQ, and SQ

30:26 – How Fear Drives VC Pattern Matching

33:01 – Why Structural Gaps Create Outlier Opportunities

35:14 – Finding Startup Capital Outside Traditional VC

38:09 – Why Founders Need to Understand Their “Why”

Hosted by Isabelle Johannesen. Produced and edited by Maggie Nye. Audience development led by Morgan Little. Special thanks to the Foundry and Cheddar video teams.

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Science & Technology

The High Risk, High Reward Model of Backing Immigrant Founders l Build Mode

Immigrant founders have built some of the world’s most valuable companies, but many still face barriers that make it harder to get a startup off the ground. Visa restrictions, limited access to friends-and-family capital, shallow networks, and a venture industry built around pattern matching can keep promising founders from getting funded before they have a…

Published

on

Immigrant founders have built some of the world’s most valuable companies, but many still face barriers that make it harder to get a startup off the ground. Visa restrictions, limited access to friends-and-family capital, shallow networks, and a venture industry built around pattern matching can keep promising founders from getting funded before they have a chance to prove themselves.

In this episode of Build Mode, host Isabelle Johannesen sits down with Manan Mehta, co-founder and managing partner of Unshackled Ventures, to talk about why he believes immigrant founders represent one of venture capital’s biggest overlooked opportunities. Manan breaks down how Unshackled built an investment model designed to help founders navigate immigration barriers, why traditional VC pattern matching causes investors to miss potential outliers, and how his team evaluates founders at day zero—often before they have a product, customers, or traction. He also explains why the structural gaps that make some founders harder to fund may be exactly where investors should be looking for outsized returns.

Subscribe to Build Mode:
Apple Podcasts
Spotify
Wherever you like to listen
New episodes of Build Mode drop every Thursday.

Chapters:
00:00 – Why VCs Miss Outlier Founders
01:45 – Why Manan Mehta Founded Unshackled Ventures
04:15 – The Problem With VC Pattern Matching
06:15 – The Friends-and-Family Gap for Immigrant Founders
08:18 – How Unshackled Helps Founders Navigate Visas
10:40 – Building a Startup in Today’s Immigration Environment
12:19 – Solving One of Unshackled’s Hardest Immigration Cases
14:39 – What the U.S. Stands to Lose
16:59 – Raising Unshackled’s First Venture Funds
19:40 – Can You Start a Company on an H-1B Visa?
22:13 – How to Evaluate a Founder at Day Zero
28:30 – Measuring IQ, AQ, EQ, and SQ
30:26 – How Fear Drives VC Pattern Matching
33:01 – Why Structural Gaps Create Outlier Opportunities
35:14 – Finding Startup Capital Outside Traditional VC
38:09 – Why Founders Need to Understand Their “Why”

Hosted by Isabelle Johannesen. Produced and edited by Maggie Nye. Audience development led by Morgan Little. Special thanks to the Foundry and Cheddar video teams.

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Science & Technology

Hands-on With Google’s New Pixel 11 Devices

Get a hands-on look at Google’s new Pixel 11 lineup, from the more durable Pro Fold, an updated new camera bar, and of course, a push for Gemini AI features.

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Get a hands-on look at Google’s new Pixel 11 lineup, from the more durable Pro Fold, an updated new camera bar, and of course, a push for Gemini AI features.

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